Zhang Ying, Chen Kaimin, Cao Lan, Li Kai, Wang Qiaoling, Fu Enyu, Guo Xuhong
State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China.
Polymers (Basel). 2019 May 7;11(5):816. doi: 10.3390/polym11050816.
Pickering emulsions are increasingly applied in drug delivery, oil-water separation, composite materials preparation, and other fields. However, systematic studies on the stabilization of Pickering emulsions to satisfy the growing application demands in multiple fields with long-term conservation are rare. Compared to conventional solid nanoparticles, polyanion-modified hairy nanoparticles are more stable in practical environments and are investigated in this study. Poly (sodium -styrenesulfonate) was grafted to a polystyrene (PS) core via a photoemulsion polymerization. A hairy nanoparticle bearing polyanions called poly (sodium -styrenesulfonate) brush (PS@PSS) was synthesized. The size and uniformity of the Pickering emulsions stabilized by PS@PSS were investigated via a polarizing microscope. The stability of Pickering emulsions were optimized by adjusting critical factors like ultrasonic power and time, standing time, oil phases, salt concentration, and water:oil ratio. Results indicated that the Pickering emulsions could be stabilized by PS@PSS nanoparticles, which showed remarkable and adjustable partial wetting properties. It was found that the optimized conditions were ultrasonic power of 150 W, ultrasonic time of 3 min, salt concentration of 0.1 mM, oil phase of hexadecane, and water:oil ratio of 1:1. The formation and stability of Pickering emulsion are closely related to the hairy poly (sodium -styrenesulfonate) brush layer on the nanoparticle surface.
皮克林乳液在药物递送、油水分离、复合材料制备等领域的应用日益广泛。然而，针对皮克林乳液的稳定性进行系统研究以满足多领域不断增长的长期保存应用需求的情况却很少见。与传统固体纳米颗粒相比，聚阴离子修饰的毛发状纳米颗粒在实际环境中更稳定，本研究对其进行了探究。通过光乳液聚合将聚（苯乙烯磺酸钠）接枝到聚苯乙烯（PS）核上。合成了一种带有聚阴离子的毛发状纳米颗粒，即聚（苯乙烯磺酸钠）刷（PS@PSS）。通过偏光显微镜研究了由PS@PSS稳定的皮克林乳液的尺寸和均匀性。通过调整超声功率和时间、静置时间、油相、盐浓度以及水油比等关键因素来优化皮克林乳液的稳定性。结果表明，PS@PSS纳米颗粒能够稳定皮克林乳液，其表现出显著且可调节的部分润湿特性。研究发现，优化条件为超声功率150 W、超声时间3 min、盐浓度0.1 mM、油相为十六烷以及水油比为1:1。皮克林乳液的形成和稳定性与纳米颗粒表面的毛发状聚（苯乙烯磺酸钠）刷层密切相关。
