Studer D, Hasler C
Universitätskinderspital beider Basel, UKBB, Spitalstrasse 33, 4056, Basel, Schweiz.
Orthopade. 2019 Jun;48(6):469-476. doi: 10.1007/s00132-019-03739-0.
The majority of growth disturbances of the spine are acquired and their etiology is still unknown. Both scolioses and sagittal profile disorders are most commonly of idiopathic origin.
The etiology is multifactorial and besides genetic, hormonal and mechanical factors also metabolic components seem to be involved. The risk of progression of an existing deformity is particularly high during the pubertal growth spurt. Accordingly, regular clinical and radiological controls should be carried out in this vulnerable period. Recently, spinal deformities have been classified according to the time of diagnosis rather than according to their etiology, considering the increasing knowledge about the correlation between spinal and thoracic growth and the associated maturation of the lungs. Therefore, the term "early onset scoliosis" considers all deformities of the spine diagnosed before the age of 10 years.
In the case of failure of conservative treatment options, which have to be applied for as long as possible, definitive spinal fusion surgery should be delayed by the use of growth-sparing surgical techniques, aiming to achieve as normal pulmonary function as possible.
脊柱生长紊乱大多是后天获得性的,其病因尚不清楚。脊柱侧弯和矢状面畸形最常见的病因是特发性的。
病因是多因素的,除了遗传、激素和机械因素外,代谢成分似乎也有影响。在青春期生长突增期间,现有畸形进展的风险特别高。因此,在这个易发病时期应定期进行临床和放射学检查。近来,考虑到对脊柱和胸廓生长以及肺相关成熟度之间相关性的认识不断增加,脊柱畸形已根据诊断时间而非病因进行分类。因此,“早发性脊柱侧弯”一词涵盖所有在10岁之前诊断出的脊柱畸形。
对于必须尽可能长时间采用的保守治疗方法失败的情况,应通过采用保留生长的手术技术推迟确定性脊柱融合手术,目标是尽可能实现正常的肺功能。