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治疗异常侵袭性胎盘后自我报告的身体、心理和生殖后遗症:一项单中心观察性研究。

Self-reported physical, mental, and reproductive sequelae after treatment of abnormally invasive placenta: a single-center observational study.

机构信息

Department of Obstetrics and Gynecology, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.

出版信息

Arch Gynecol Obstet. 2019 Jul;300(1):95-101. doi: 10.1007/s00404-019-05175-z. Epub 2019 May 8.

Abstract

OBJECTIVE

To analyze the types of treatment of abnormally invasive placenta (AIP) and to investigate the self-reported physical and mental short- and long-term sequelae.

METHODS

This single-center observational study was performed between 2003 and 2017. Women with prenatal or intrapartum diagnosis of AIP were identified through the departmental database. Classification was performed according to the time of diagnosis establishment and the type of treatment. Medical complications overall and according to the type of treatment were analyzed. Data about women's perception of diagnosis, treatment, and short- and long-term sequelae were gathered by questionnaire.

RESULTS

Cases were classified into four groups: prenatal diagnosis, cesarean hysterectomy (A, n = 10); prenatal diagnosis, expectant management (B, n = 19); intrapartum diagnosis, cesarean hysterectomy (C, n = 6); intrapartum diagnosis, conservative therapy (D, n = 20). Depth of invasion, total units of transfused red blood cells, and the need for reoperation differed between the treatment groups. Expectant management was successful in 94.7% of cases. Irrespective of the treatment group, 73.3% of women perceived the condition as serious or life-threatening; 30.0% utilized psychological support; and 36.7% reported persistent pain or problems. 37.5% of women after uterine preservation had another live birth, AIP recurred in 44.4% of cases.

CONCLUSION

Conservative management of AIP is feasible in selected cases. The condition is perceived as life-threatening and has a lasting impact on the physical, mental, and reproductive health of those affected. This finding merits further investigation. AIP continues to be a condition with high morbidity.

摘要

目的

分析异常性胎盘植入(AIP)的治疗类型,并探讨其自我报告的身心短期和长期后遗症。

方法

本单中心观察性研究于 2003 年至 2017 年进行。通过科室数据库确定产前或产时诊断为 AIP 的女性。根据诊断确立的时间和治疗类型进行分类。分析整体和根据治疗类型的医疗并发症。通过问卷调查收集有关女性对诊断、治疗和短期及长期后遗症的看法。

结果

病例分为四组:产前诊断、剖宫产子宫切除术(A 组,n=10);产前诊断、期待治疗(B 组,n=19);产时诊断、剖宫产子宫切除术(C 组,n=6);产时诊断、保守治疗(D 组,n=20)。各组的入侵深度、输注的红细胞单位总数和再次手术的需求不同。期待治疗成功率为 94.7%。无论治疗组如何,73.3%的女性认为病情严重或危及生命;30.0%需要心理支持;36.7%报告持续疼痛或问题。37.5%保留子宫的女性再次分娩,44.4%的病例 AIP 复发。

结论

在选定的病例中,AIP 的保守治疗是可行的。该疾病被认为是危及生命的,对受影响者的身体、心理和生殖健康产生持久影响。这一发现值得进一步研究。AIP 仍然是一种发病率较高的疾病。

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