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对患有胎盘植入、穿透性胎盘植入和侵入性胎盘植入的女性预防性使用血管内球囊导管。

Prophylactic use of intravascular balloon catheters in women with placenta accreta, increta and percreta.

作者信息

Cali Giuseppe, Forlani Francesco, Giambanco Laura, Amico Maria Luisa, Vallone Mario, Puccio Giuseppe, Alio Luigi

机构信息

Department of Obstetrics and Gynecology, Arnas Civico, Di Cristina e Benfratelli, Palermo, Italy.

Department of Obstetrics and Gynecology, University Hospital "Paolo Giaccone", Alfonso Giordano 3, Palermo 90100, Italy.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2014 Aug;179:36-41. doi: 10.1016/j.ejogrb.2014.05.007. Epub 2014 May 21.

Abstract

OBJECTIVE

To evaluate outcomes of women undergoing cesarean hysterectomy for abnormal invasive placenta (AIP) with and without preoperative balloon catheter placement in internal iliac arteries.

STUDY DESIGN

A prospective observational study of women with ultrasound diagnosis of AIP and a planned delivery at our institution. From January 2004 to June 2009, all AIP cases were treated with planned multidisciplinary cesarean hysterectomy alone (CHa group). From July 2009 to September 2013 a pre-operative balloon catheter protocol was introduced (BC group). Statistical analysis considered the entire sample (placenta accreta/increta and percreta) and the individual subgroups (accreta/increta vs percreta).

RESULTS

Twenty-three cases of AIP (10 accreta/increta and 13 percreta) were treated with cesarean hysterectomy alone, and 30 cases of AIP (12 accreta/increta and 18 percreta) were treated with cesarean hysterectomy and pre-operative balloon catheters. For the entire sample, a significant difference in estimated blood loss and transfused blood products units was observed between CHa group and BC group. When women with placenta accreta/increta and women with placenta percreta were analysed separately, no difference in estimated blood loss and transfused blood products units was found between the BC and the CHa groups in women with placenta accreta/increta. However, in women with placenta percreta, mean estimated blood loss and transfused blood products units were higher in the CHa group compared with BC group (1507ml vs 933.33ml; 3.31 units vs 0.67 units). Postoperative recovery differed between the two groups, but no differences were observed in any other outcomes.

CONCLUSIONS

Pre-operative placement of intravascular balloon catheters is a feasible treatment for AIP, and is particularly useful in cases of placenta percreta.

摘要

目的

评估接受剖宫产子宫切除术治疗异常侵袭性胎盘(AIP)的女性患者,术前髂内动脉放置球囊导管与未放置球囊导管的治疗效果。

研究设计

对我院超声诊断为AIP且计划分娩的女性患者进行前瞻性观察研究。2004年1月至2009年6月,所有AIP病例仅接受计划性多学科剖宫产子宫切除术(CHa组)。2009年7月至2013年9月引入术前球囊导管方案(BC组)。统计分析考虑了整个样本(胎盘植入/侵入性胎盘和穿透性胎盘)以及各个亚组(植入/侵入性胎盘与穿透性胎盘)。

结果

23例AIP患者(10例植入/侵入性胎盘和13例穿透性胎盘)仅接受剖宫产子宫切除术治疗,30例AIP患者(12例植入/侵入性胎盘和18例穿透性胎盘)接受剖宫产子宫切除术及术前球囊导管治疗。对于整个样本,CHa组和BC组在估计失血量和输注血液制品单位方面存在显著差异。当分别分析植入/侵入性胎盘女性和穿透性胎盘女性时,植入/侵入性胎盘女性的BC组和CHa组在估计失血量和输注血液制品单位方面未发现差异。然而,在穿透性胎盘女性中,CHa组的平均估计失血量和输注血液制品单位高于BC组(1507ml对933.33ml;3.31单位对0.67单位)。两组术后恢复情况不同,但在任何其他结局方面未观察到差异。

结论

术前血管内球囊导管置入是治疗AIP的一种可行方法,对穿透性胎盘病例尤其有用。

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