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[血液中T淋巴细胞和B淋巴细胞差异的荧光探针指示剂]

[Fluorescent probe-indicator of differences between T- and B-lymphocytes in the blood].

作者信息

Dobretsov G E, Korkina L G, Val'tsel' G, Zimin Iu I, Kogan E M

出版信息

Biull Eksp Biol Med. 1979 Jan;87(1):51-3.

PMID:310696
Abstract

A new physico-chemical marker for the human peripheral blood lymphocytes was worked out. The lymphocytes were vitally stained with the fluorescent probe 3-methoxybenzanthrone and measured by microfluorometry. The blood lymphocytes population was found to be heterogeneous; this population consists of the two main groups of cells differing by the intensity of their fluorescence. By means of immunological lymphocyte fractionation it was shown that one of these cell groups was represented by T-lymphocytes, and the other one--by B-lymphocytes.

摘要

一种用于人类外周血淋巴细胞的新的物理化学标记物被研制出来。用荧光探针3-甲氧基苯并蒽对淋巴细胞进行活体染色,并通过显微荧光测定法进行测量。发现血液淋巴细胞群体是异质性的;该群体由两组主要细胞组成,它们的荧光强度不同。通过免疫淋巴细胞分级分离表明,这些细胞组中的一组由T淋巴细胞代表,另一组由B淋巴细胞代表。

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1
[Fluorescent probe-indicator of differences between T- and B-lymphocytes in the blood].[血液中T淋巴细胞和B淋巴细胞差异的荧光探针指示剂]
Biull Eksp Biol Med. 1979 Jan;87(1):51-3.
2
[Ryodipine--a new fluorescent probe in the determination of differences between lymphocytes].[利奥地平——用于测定淋巴细胞差异的新型荧光探针]
Biull Eksp Biol Med. 1989 Nov;108(11):597-600.
3
[Determination of the surface area and viscosity of membranes in T- and B-lymphocytes by means of fluorescent probes].
Biofizika. 1983 Jan-Feb;28(1):142-4.
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Membrane fluorescent probes for revealing lymphocyte population heterogeneity. II. T-and B-lymphocytes of human peripheral blood.用于揭示淋巴细胞群体异质性的膜荧光探针。II. 人外周血中的T淋巴细胞和B淋巴细胞。
J Immunol Methods. 1982 Mar 12;49(2):179-83. doi: 10.1016/0022-1759(82)90275-7.
5
[Differences between lymphocytes revealed by membrane fluorescent probes].[膜荧光探针揭示的淋巴细胞间差异]
Tsitologiia. 1980 Mar;22(3):320-5.
6
[Identification of T- and B-lymphocytes using a 3-methoxybenzanthrone fluorescent probe].
Dokl Akad Nauk SSSR. 1978;238(4):999-1002.
7
[Differences in leukocyte membranes detectable by a fluorescent probe in chronic leukemias].
Biull Eksp Biol Med. 1982 Apr;93(4):35-7.
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Membrane fluorescent probes for the demonstration of lymphocyte population heterogeneity. I T. and B lymphocytes of mice and rats.用于显示淋巴细胞群体异质性的膜荧光探针。I. 小鼠和大鼠的T淋巴细胞和B淋巴细胞。
J Immunol Methods. 1981;45(3):227-37. doi: 10.1016/0022-1759(81)90301-x.
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HLA-DRw alloantigens can be detected on peripheral blood T lymphocytes.HLA - DRw同种异体抗原可在外周血T淋巴细胞上被检测到。
J Immunol. 1980 Nov;125(5):1889-96.
10
Hydrophobic probe's fluorescence intensity. 3-methoxybenzanthrone (3-MBA) in bronchial asthma and urticaria patients lymphocyte membranes.疏水探针的荧光强度。支气管哮喘和荨麻疹患者淋巴细胞膜中的3-甲氧基苯并蒽酮(3-MBA)。
Allergol Immunopathol (Madr). 1988 Jul-Aug;16(4):237-42.