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Current Landscape of Heart Failure Gene Therapy.

作者信息

Kieserman Jake M, Myers Valerie D, Dubey Praveen, Cheung Joseph Y, Feldman Arthur M

机构信息

1 Division of Cardiology The Department of Medicine Lewis Katz School of Medicine at Temple University Philadelphia PA.

出版信息

J Am Heart Assoc. 2019 May 21;8(10):e012239. doi: 10.1161/JAHA.119.012239.

DOI:10.1161/JAHA.119.012239
PMID:31070089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6585330/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7663/6585330/06b56548eeec/JAH3-8-e012239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7663/6585330/06b56548eeec/JAH3-8-e012239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7663/6585330/06b56548eeec/JAH3-8-e012239-g001.jpg

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Current Landscape of Heart Failure Gene Therapy.心力衰竭基因治疗的现状
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Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations.BAG3 相关扩张型心肌病
J Am Coll Cardiol. 2018 Nov 13;72(20):2471-2481. doi: 10.1016/j.jacc.2018.08.2181.
2
Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.BAG3 变异与非裔美国人个体中心肌病结局的关联。
JAMA Cardiol. 2018 Oct 1;3(10):929-938. doi: 10.1001/jamacardio.2018.2541.
3
Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal.促肾上腺皮质激素释放因子2与促肾上腺皮质激素释放因子3基因转移对左心室功能和葡萄糖代谢的影响。
心脏桥接整合因子1基因疗法可挽救小型猪的慢性非缺血性心力衰竭。
NPJ Regen Med. 2024 Dec 10;9(1):36. doi: 10.1038/s41536-024-00380-0.
4
When Off-Target the Target: Treating Noncardiomyocytes in Cardiac Laminopathy.当偏离靶点时针对靶点：治疗心脏核纤层蛋白病中的非心肌细胞
JACC Basic Transl Sci. 2024 Nov 25;9(11):1326-1328. doi: 10.1016/j.jacbts.2024.09.012. eCollection 2024 Nov.
5
Regulation of β-Adrenergic Receptors in the Heart: A Review on Emerging Therapeutic Strategies for Heart Failure.β-肾上腺素受体在心脏中的调控：心力衰竭治疗新策略的综述。
Cells. 2024 Oct 10;13(20):1674. doi: 10.3390/cells13201674.
6
Advances in the Insulin-Heart Axis: Current Therapies and Future Directions.胰岛素-心脏轴的进展：当前治疗方法和未来方向。
Int J Mol Sci. 2024 Sep 22;25(18):10173. doi: 10.3390/ijms251810173.
7
Functional analysis of a common BAG3 allele associated with protection from heart failure.常见 BAG3 等位基因与心力衰竭保护相关的功能分析。
Nat Cardiovasc Res. 2023 Jul;2(7):615-628. doi: 10.1038/s44161-023-00288-w. Epub 2023 Jun 26.
8
Precision Genetic Therapies: Balancing Risk and Benefit in Patients with Heart Failure.精准基因治疗：心力衰竭患者的风险与获益平衡。
Curr Cardiol Rep. 2024 Sep;26(9):973-983. doi: 10.1007/s11886-024-02096-5. Epub 2024 Aug 7.
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Progress in the treatment of diabetic cardiomyopathy, a systematic review.糖尿病心肌病的治疗进展：系统评价。
Pharmacol Res Perspect. 2024 Apr;12(2):e1177. doi: 10.1002/prp2.1177.
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Emerging Strategies and Effective Prevention Measures for Investigating the Association Between Stroke and Sudden Cardiac Fatality.探索中风与心源性猝死之间关联的新兴策略和有效预防措施。
Curr Cardiol Rev. 2024;20(3):35-44. doi: 10.2174/011573403X259676231222053709.
JACC Basic Transl Sci. 2018 May 30;3(2):249-264. doi: 10.1016/j.jacbts.2017.12.004. eCollection 2018 Apr.
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Urocortin 3 Gene Transfer Increases Function of the Failing Murine Heart.尿皮质素 3 基因转移增加衰竭的小鼠心脏功能。
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