Pharmacy Practice, JKKN College of Pharmacy, Namakkal, India.
Department of Pharmaceutics, Vellalar College of Pharmacy, Erode, India.
Curr Cardiol Rev. 2024;20(3):35-44. doi: 10.2174/011573403X259676231222053709.
Stroke-related cardiac death is a significant concern for patients with stroke and their healthcare providers. It is a complex and multifaceted condition that requires careful management of both modifiable and non-modifiable risk factors. This review provides an overview of the pathophysiology, risk factors, and prevention strategies for stroke-related cardiac death. The review highlights the importance of identifying and managing modifiable risk factors such as hypertension, diabetes, and lifestyle factors, as well as non-modifiable risk factors such as age and genetics. Additionally, the review explores emerging strategies for prevention, including the use of wearable devices and genetic testing to identify patients at risk, stem cell therapy and gene therapy for cardiac dysfunction, and precision medicine for personalized treatment plans. Despite some limitations to this review, it provides valuable insights into the current understanding of stroke-related cardiac death and identifies important areas for future research. Ultimately, the implementation of evidence-based prevention strategies and personalized treatment plans has the potential to improve outcomes for patients with stroke and reduce the burden of stroke-related cardiac death in the population.
与中风相关的心脏性死亡是中风患者及其医疗保健提供者关注的一个重要问题。这是一种复杂且多方面的疾病,需要仔细管理可改变和不可改变的风险因素。这篇综述提供了与中风相关的心脏性死亡的病理生理学、风险因素和预防策略概述。该综述强调了识别和管理可改变风险因素(如高血压、糖尿病和生活方式因素)以及不可改变风险因素(如年龄和遗传)的重要性。此外,该综述探讨了预防的新策略,包括使用可穿戴设备和基因测试来识别有风险的患者、针对心脏功能障碍的干细胞治疗和基因治疗,以及用于个性化治疗计划的精准医学。尽管本综述存在一些局限性,但它为我们目前对与中风相关的心脏性死亡的理解提供了有价值的见解,并确定了未来研究的重要领域。最终,实施基于证据的预防策略和个性化治疗计划有可能改善中风患者的预后,并降低人群中与中风相关的心脏性死亡的负担。