Jörg J, Janssen A
Z Gerontol. 1987 Jan-Feb;20(1):38-43.
After a short summary of the leading symptoms, the neuropathological and the pathobiochemical findings in Parkinson's disease, the possibilities of pharmacological treatment are pointed out. The choice of the suitable medication depends on the stage and severity of the disorder and the leading symptoms. Medical side-effects and contraindications of the different antiparkinsonica must be considered. Problems of long-term medication especially of L-dopa are discussed. Examples of reasonable "combined therapies" are given allowing the attempt to reduce the L-dopa dose without losing treatment effectiveness. In addition to the pharmacological treatment and for special indications, surgical i.e. stereotactic manipulations, intensive physiosocial care, physiotherapy and logotherapy are very necessary.
在简要总结帕金森病的主要症状、神经病理学和病理生物化学发现之后，指出了药物治疗的可能性。合适药物的选择取决于疾病的阶段和严重程度以及主要症状。必须考虑不同抗帕金森病药物的医学副作用和禁忌证。讨论了长期用药尤其是左旋多巴的问题。给出了合理“联合治疗”的例子，以便在不丧失治疗效果的情况下尝试减少左旋多巴剂量。除了药物治疗以及针对特殊适应证外，手术即立体定向操作、强化的社会心理护理、物理治疗和言语治疗也非常必要。
