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甲型肝炎后发生的严重再生障碍性贫血。

Severe aplastic anaemia following hepatitis A.

作者信息

Doménech P, Palomeque A, Martínez-Gutiérrez A, Viñolas N, Vela E, Jiménez R

出版信息

Acta Haematol. 1986;76(4):227-9. doi: 10.1159/000206061.

DOI:10.1159/000206061
PMID:3107310
Abstract

A 3-year-old child developed severe aplastic anaemia following hepatitis A. Since no HLA-compatible donor was available, he was treated with oxymetholone, antithymocytic globulin and methylprednisolone, but no haematologic recovery was observed and he consequently died of pneumonia. Although the association of aplastic anaemia and hepatitis A has already been recognized, this patient represents the first case of aplastic anaemia in which the previous hepatitis A has been well documented.

摘要

一名3岁儿童在患甲型肝炎后出现严重再生障碍性贫血。由于没有HLA匹配的供体,他接受了羟甲烯龙、抗胸腺细胞球蛋白和甲泼尼龙治疗,但未观察到血液学恢复,最终死于肺炎。尽管再生障碍性贫血与甲型肝炎的关联已得到认可,但该患者是首例先前甲型肝炎有充分记录的再生障碍性贫血病例。

相似文献

1
Severe aplastic anaemia following hepatitis A.甲型肝炎后发生的严重再生障碍性贫血。
Acta Haematol. 1986;76(4):227-9. doi: 10.1159/000206061.
2
Post-hepatitic aplastic anaemia in children in Taiwan, a hepatitis prevalent area.台湾儿童肝炎后再生障碍性贫血,台湾是肝炎高发地区。
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Does viral hepatitis cause aplastic anaemia?病毒性肝炎会导致再生障碍性贫血吗?
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Fatal aplastic anaemia complicating infectious hepatitis.
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Aplastic anaemia. 3. Aplastic anaemia and infectious hepatitis.
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[Successful treatment of a case of hepatitis-associated severe aplastic anemia by anti-lymphocyte globulin (ALG)].[抗淋巴细胞球蛋白(ALG)成功治疗1例肝炎相关性重型再生障碍性贫血]
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Hepatitis-associated aplastic anaemia treated successfully with antilymphocyte globulin.用抗淋巴细胞球蛋白成功治疗的肝炎相关性再生障碍性贫血。
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引用本文的文献

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Hepatitis-associated Aplastic Anemia with Rapid Progression of Liver Fibrosis Due to Repeated Hepatitis.反复肝炎所致肝纤维化快速进展的肝炎相关性再生障碍性贫血
Intern Med. 2020 Apr 15;59(8):1035-1040. doi: 10.2169/internalmedicine.4072-19. Epub 2019 Dec 26.
2
Acute hepatitis A induction of precursor B-cell acute lymphoblastic leukemia: a causal relationship?甲型肝炎诱发前体B细胞急性淋巴细胞白血病:存在因果关系吗?
Case Rep Oncol. 2010 Sep;3(3):505-9. doi: 10.1159/000323487. Epub 2010 Dec 24.
3
Hepatitis-associated aplastic anemia during a primary infection of genotype 1a torque teno virus.
1a 型扭转型肝炎病毒初次感染期间伴发肝炎相关性再生障碍性贫血。
Eur J Pediatr. 2010 Jul;169(7):899-902. doi: 10.1007/s00431-009-1116-8. Epub 2009 Dec 9.
4
Hepatitis associated with aplastic anemia: do CD8(+) kupffer cells have a role in the pathogenesis?与再生障碍性贫血相关的肝炎:CD8(+) 库普弗细胞在发病机制中起作用吗?
Dig Dis Sci. 2007 Sep;52(9):2438-43. doi: 10.1007/s10620-006-9280-4. Epub 2007 Apr 19.
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Hepatitis A virus suppresses monocyte-to-macrophage maturation in vitro.甲型肝炎病毒在体外抑制单核细胞向巨噬细胞的成熟。
J Virol. 2002 May;76(9):4350-6. doi: 10.1128/jvi.76.9.4350-4356.2002.
6
Hepatitis A: old and new.甲型肝炎:新旧情况
Clin Microbiol Rev. 2001 Jan;14(1):38-58. doi: 10.1128/CMR.14.1.38-58.2001.
7
Severe aplastic anemia associated with seronegative community-acquired hepatitis C virus infection.与血清学阴性的社区获得性丙型肝炎病毒感染相关的严重再生障碍性贫血。
Ann Hematol. 1993 Mar;66(3):157-9. doi: 10.1007/BF01697628.