Bestari Muhammad Begawan, Laksono Bayu
Division of Gastroenterohepatology Department of Internal Medicine Faculty of Medicine - University of Padjadjaran Hasan Sadikin General Hospital Bandung - Indonesia.
Acta Med Indones. 2019 Jan;51(1):86-92.
Endoscopic procedure is commonly used to make diagnosis or therapy. Endoscopy has risk on the procedure or after the procedure. Patient with antithrombotic therapy, both antiplatelet and/or anticoagulant, for underlying diseases has higher risk for bleeding and thromboembolic events in this procedure. The physician should consider risk and benefit for adjusting the antithrombotic therapy, in addition to minimize bleeding and thromboembolic events. For low risk procedure, adjustments in antithrombotic therapy usually not necessarily needed. For high risk procedure, there are several adjustments based on the type of medication and patient's condition in specific. European Society of Gastrointestinal Guidelines Endoscopy (ESGE) and British Society of Gastrointestinal (BSG); American Society of Gastrointestinal Endoscopy (ASGE); and lastly Asian Pacific Association of Gastroenterology (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) have published guidelines to help physician to make decisions regarding antithrombotic therapy management during endoscopy. This article compares and contrasts the approach of each guideline, in design to help the decision-making process. However, each patient's clinical condition may differ from one to another and should be considered carefully in making a final decision.
内镜检查程序常用于诊断或治疗。内镜检查在操作过程中或操作后存在风险。正在接受抗血栓治疗(包括抗血小板和/或抗凝治疗)以治疗基础疾病的患者,在此检查过程中发生出血和血栓栓塞事件的风险更高。除了尽量减少出血和血栓栓塞事件外,医生在调整抗血栓治疗时应考虑风险和益处。对于低风险操作,通常不一定需要调整抗血栓治疗。对于高风险操作,则需要根据具体的药物类型和患者情况进行多种调整。欧洲胃肠内镜学会(ESGE)、英国胃肠学会(BSG)、美国胃肠内镜学会(ASGE),以及亚太胃肠病学会(APAGE)和亚太消化内镜学会(APSDE)都发布了相关指南,以帮助医生在内镜检查期间做出关于抗血栓治疗管理的决策。本文比较并对比了各指南的方法,旨在帮助决策过程。然而,每个患者的临床情况可能各不相同,在做出最终决定时应仔细考虑。