Belai Natnael, Ghebrenegus Amon Solomon, Alamin Amin Ata, Alamin Anim Ata, Embaye Ghirmay, Andegiorgish Amanuel Kidane
Orotta National Medical Surgical Referral Teaching Hospital, Asmara, Eritrea.
Ghindae Zonal Referral Hospital, Ghindae, Eritrea.
BMC Hematol. 2019 May 2;19:8. doi: 10.1186/s12878-019-0138-3. eCollection 2019.
Even though the incidences of hematologic malignancies have received considerable attentions globally, there is paucity of information on patterns of hematologic malignancy in Eritrea. The study was conducted to determine the distribution of various hematologic malignancies among patients who have received bone marrow examination, in the Eritrean National Health Laboratory.
A retrospective descriptive study design was used to determine the patterns of Hematologic malignancies diagnosed at the Eritrean National Health Laboratory from October 2015 to July 2017.
Out of 207 patients who did bone marrow aspiration 52 patients were hematologic malignancy cases. The male to female ratio was 1:1. The age of the patients ranged from 2 to 80 years. Of the 52 patients 19, were less than 20 years of age and the remaining 33 were 20 years and above. Acute leukemia was the most common hematologic malignancy in the study area. It affected 18 of the cases followed by chronic myelogenous leukemia, chronic lymphocytic leukemia, myelodysplastic syndromes, multiple myeloma, and myeloprofilerative neoplasms. The presenting signs and symptoms in their decreasing frequency were generalized body weakness/fatigue, splenomegaly, fever, anemia, and lymphadenopathy. More than two-third of the patients had total leukocyte count greater than 10,000/μl.
This study shows that hematologic malignancies are not uncommon in Eritrea.
尽管血液系统恶性肿瘤的发病率在全球范围内受到了广泛关注，但厄立特里亚关于血液系统恶性肿瘤模式的信息却很匮乏。本研究旨在确定在厄立特里亚国家卫生实验室接受骨髓检查的患者中各种血液系统恶性肿瘤的分布情况。
采用回顾性描述性研究设计，以确定2015年10月至2017年7月在厄立特里亚国家卫生实验室诊断出的血液系统恶性肿瘤模式。
在207例进行骨髓穿刺的患者中，有52例为血液系统恶性肿瘤病例。男女比例为1:1。患者年龄范围为2至80岁。在这52例患者中，19例年龄小于20岁，其余33例年龄在20岁及以上。急性白血病是研究区域最常见的血液系统恶性肿瘤。它影响了18例病例，其次是慢性粒细胞白血病、慢性淋巴细胞白血病、骨髓增生异常综合征、多发性骨髓瘤和骨髓增殖性肿瘤。出现频率从高到低的体征和症状依次为全身无力/疲劳、脾肿大、发热、贫血和淋巴结病。超过三分之二的患者白细胞总数大于10,000/μl。
本研究表明血液系统恶性肿瘤在厄立特里亚并不罕见。
