蚕豆病患者的白细胞增多症与输血的关系。
Leukocytosis in patients with favism and association with blood transfusion.
机构信息
Faculty of Medicine, Department of Pediatrics, Lorestan University of Medical Sciences, Khorramabad, Iran.
Student of Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
出版信息
J Clin Lab Anal. 2019 Jul;33(6):e22906. doi: 10.1002/jcla.22906. Epub 2019 May 9.
INTRODUCTION
Leukocytosis is a condition marked by abnormal increase in leukocyte count due to an inflammatory response as a defense against most of the infections, or bone tumors; including leukemia. The aim of this study is to analyze the effect of blood transfusion in leukocytosis patients with favism as compared to patients treated with antibiotics or combination of both.
METHODS
A total of 97 patients with favism who were referred to the University hospital in 2016-2017 were studied.
KEY FINDINGS
These patients experienced acute hemolysis following beans meal. These patients were either treated with blood transfusion, antibiotics or combination of both.
CONCLUSIONS
This study shows that blood transfusion is an effective therapeutic option for the treatment of leukocytosis. Antibiotics are not deemed necessary for the treatment and blood transfusion alone, can decrease leukocytes to the normal level.
简介
白细胞增多症是一种由于炎症反应导致白细胞计数异常增加的病症，这种反应是机体对大多数感染或骨肿瘤（包括白血病）的防御机制。本研究旨在分析输血对伴有蚕豆病的白细胞增多症患者的影响，并与接受抗生素或两者联合治疗的患者进行比较。
方法
本研究共纳入了 2016 年至 2017 年期间被转诊至大学医院的 97 名蚕豆病患者。
主要发现
这些患者在食用豆类后出现急性溶血。这些患者分别接受输血、抗生素或两者联合治疗。
结论
本研究表明，输血是治疗白细胞增多症的有效治疗选择。抗生素治疗并非必需，单独输血即可使白细胞降至正常水平。
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