Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, China.
National Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang 330022, China.
Chem Rev. 2019 Jun 26;119(12):6769-6787. doi: 10.1021/acs.chemrev.9b00045. Epub 2019 May 10.
Photo-/electrochemical catalyzed oxidative R-H/R-H cross-coupling with hydrogen evolution has become an increasingly important issue for molecular synthesis. The dream of construction of C-C/C-X bonds from readily available C-H/X-H with release of H can be facilely achieved without external chemical oxidants, providing a greener model for chemical bond formation. Given the great influence of these reactions in organic chemistry, we give a summary of the state of the art in oxidative R-H/R-H cross-coupling with hydrogen evolution via photo/electrochemistry, and we hope this review will stimulate the development of a greener synthetic strategy in the near future.
光/电催化氧化 R-H/R-H 交叉偶联与氢析出已成为分子合成中一个日益重要的问题。通过光/电化学从易得的 C-H/X-H 构建 C-C/C-X 键并同时释放 H2 的梦想，可以在无需外加化学氧化剂的情况下轻松实现，为化学键形成提供了更绿色的模式。鉴于这些反应在有机化学中的巨大影响，我们对通过光/电化学进行的氧化 R-H/R-H 交叉偶联与氢析出反应的最新研究进展进行了总结，希望这篇综述能够激发更绿色合成策略在不久的将来的发展。
