病例报告：人类感染非洲锥虫病致 HIV-1 合并多发性骨髓瘤住院患者发热。
Case Report: Human African Trypanosomiasis as the Cause of Fever in an Inpatient with Multiple Myeloma and HIV-1 Coinfection.
机构信息
J.D. MacLean Centre for Tropical Diseases, Montreal, Canada.
Faculty of Medicine, University of British Columbia, Vancouver, Canada.
出版信息
Am J Trop Med Hyg. 2019 Jul;101(1):123-125. doi: 10.4269/ajtmh.18-0889.
We report the case of a 64-year-old woman found to have urban-acquired () human African trypanosomiasis (HAT) as the cause of sustained fever starting 9 months after returning to Canada from Democratic Republic of the Congo, in the context of concomitant multiple myeloma and HIV-1 coinfection. Approaches for the management of both clinical stages of HAT are well defined for endemic settings using current diagnostics and treatments. However, few data inform the diagnosis and management of patients with bone marrow suppression from active malignancy, recent anticancer therapy, or HIV coinfection. We discuss the implications of immunosuppression for diagnosis and management of HAT.
我们报告了一例 64 岁女性的病例，她从刚果民主共和国返回加拿大 9 个月后持续发热，被诊断为城市获得性 () 人体非洲锥虫病（HAT），同时患有多发性骨髓瘤和 HIV-1 合并感染。目前的诊断和治疗方法已经为流行地区的 HAT 两个临床阶段的管理制定了明确的方法。然而，关于因活动性恶性肿瘤、最近的抗癌治疗或 HIV 合并感染导致骨髓抑制的患者的诊断和管理，数据很少。我们讨论了免疫抑制对 HAT 诊断和管理的影响。
Zotero 插件