Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerpen, Belgium.
Expert Rev Mol Diagn. 2015 May;15(5):607-15. doi: 10.1586/14737159.2015.1027195. Epub 2015 Mar 18.
A variety of molecular diagnostic tests for human African trypanosomiasis (HAT) (sleeping sickness) has been developed. Some are effectively used for research and confirmation diagnosis in travel medicine, usually following non-standardized protocols. Others have become commercially available as diagnostic kits. WHO aims to eliminate HAT as a public health problem by the year 2020, and zero transmission by the year 2030. This article gives an overview of the recent progress in molecular diagnostics for sleeping sickness, including the most recent data on test performances. Also discussed is how molecular diagnostics can play an important role in the process toward the elimination of HAT.
已经开发出多种用于诊断人类非洲锥虫病（昏睡病）的分子诊断检测方法。其中一些方法在旅行医学中通常根据非标准化方案用于研究和确诊，另外一些则已作为诊断试剂盒上市。世卫组织的目标是在 2020 年消除作为公共卫生问题的昏睡病，并在 2030 年实现零传播。本文概述了昏睡病分子诊断方面的最新进展，包括检测性能的最新数据。本文还讨论了分子诊断如何在消除昏睡病的进程中发挥重要作用。
