Department of Medical Physics, Tehran University of Medical Sciences (TUMS), International Campus, Tehran 1416753955, Iran.
Research Center for Molecular and Cellular Imaging, TUMS, Tehran 1416753955, Iran.
Medicina (Kaunas). 2019 May 9;55(5):126. doi: 10.3390/medicina55050126.
Cardiovascular diseases (CVDs) account for the majority of deaths worldwide. Radiation-induced heart diseases (RIHD) is one of the side effects following exposure to ionizing radiation (IR). Exposure could be from various forms such as diagnostic imaging, radiotherapy for cancer treatment, as well as nuclear disasters and nuclear accidents. RIHD is mostly observed after radiotherapy for thoracic malignancies, especially left breast cancer. RIHD may affect the supply of blood to heart muscles, leading to an increase in the risk of heart attacks to irradiated persons. Due to its dose-limiting consequence, RIHD has a negative effect on the therapeutic efficacy of radiotherapy. Several methods have been proposed for protection against RIHD. In this paper, we review the use of natural products, which have shown promising results for protection against RIHD.
心血管疾病（CVDs）是全球范围内导致死亡的主要原因之一。辐射诱导的心脏疾病（RIHD）是接触电离辐射（IR）后的副作用之一。辐射源可能来自各种形式，如诊断成像、癌症放射治疗，以及核灾难和核事故。RIHD 主要发生在胸部恶性肿瘤的放射治疗后，尤其是左乳腺癌。RIHD 可能会影响心脏肌肉的血液供应，导致受照射者心脏病发作的风险增加。由于其剂量限制的后果，RIHD 对放射治疗的疗效有负面影响。已经提出了几种预防 RIHD 的方法。在本文中，我们回顾了天然产物的应用，这些天然产物在预防 RIHD 方面显示出了有希望的结果。
