含组胺和组氨酸的磷酸吡哆醛环状化合物。7：吡哆醛及含组胺和组氨酸的磷酸吡哆醛环状化合物的性质。
Phosphopyridoxal cyclic compounds with histamine and histidine. 7: The properties of pyridoxal and phosphopyridoxal cyclic compounds with histamine and histidine.
作者信息
Kierska D, Sasiak K, Maśliński C
出版信息
Agents Actions. 1978 Oct;8(5):474-7. doi: 10.1007/BF02111431.
Cyclic compounds synthesized from histamine (Hi) or histidine (His) with pyridoxal (PL)--[Hi-PL, His-PL] and Hi or His with pyridoxal 5'-phosphate (PLP)--[Hi-PLP, His-PLP] were tested for stability in buffer, acid and base solutions, crude homogenates of various tissues and in the presence of enzymes which metabolize Hi or His. The cyclic pyridoxal compounds were stable in all experimental conditions, whereas phosphopyridoxal cyclic products were degraded by rat intestinal DAO and rat intestine homogenate, apparently enzymatically. In acidic and basic solutions changes in migration velocity and u.v. absorption spectrum occur. The characteristic fluorescence of these cyclic compounds is described.
对由组胺（Hi）或组氨酸（His）与吡哆醛（PL）合成的环状化合物——[Hi-PL，His-PL]以及Hi或His与磷酸吡哆醛（PLP）合成的环状化合物——[Hi-PLP，His-PLP]，在缓冲液、酸性和碱性溶液、各种组织的粗匀浆以及存在代谢Hi或His的酶的情况下进行了稳定性测试。环状吡哆醛化合物在所有实验条件下均稳定，而磷酸吡哆醛环状产物在大鼠肠道DAO和大鼠肠道匀浆中会被降解，显然是通过酶促作用。在酸性和碱性溶液中，迁移速度和紫外吸收光谱会发生变化。描述了这些环状化合物的特征荧光。
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