Ichimaru Naotsugu, Kawamura Masataka, Nakazawa Shigeaki, Kato Taigo, Abe Toyofumi, Kaimori Jun-Ya, Imamura Ryoichi, Moriyama Toshiki, Nonomura Norio
Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Japan.
Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan.
Transplant Proc. 2019 Jun;51(5):1362-1364. doi: 10.1016/j.transproceed.2019.03.021. Epub 2019 May 7.
Dietary restriction of protein, salt, and energy is recommended to prevent lifestyle related diseases, proteinuria, and graft dysfunction in kidney transplant patients. It is useful if the patients can evaluate meal components by themselves for each meal.
A total of 26 maintenance-phase kidney transplant patients were included in the study. The mean age, sex, body mass index, number of years post-transplantation, creatinine clearance, and 24-hour urinary excretion (24 UE) of protein were recorded on a medical chart. Estimated daily protein and salt oral intake were calculated from 24 UE of nitrogen and sodium, respectively. We compared these laboratory results and patients' self-reported dietary intake using a smartphone-based recipe nutrition calculator (SRNC).
Estimated daily protein and salt oral intake calculated from 24 UE of nitrogen and sodium were 55.4 ± 12.9 g/d and 8.5 ± 3.1 g/d, respectively. Estimated daily protein and salt oral intake measured by SRNC were 52.4 ± 13.8 g/day and 6.5 ± .9 g/day, respectively. The results of estimated daily protein and salt oral intake measured by SRNC were correlated to those calculated from 24 UE (R = .287 and .217, respectively).
The results of estimated daily protein and salt oral intake measured by SRNC were correlated to those calculated from 24 UE in maintenance-phase kidney transplant patients. SRNC was useful as a measurement modality to evaluate the adherence to dietary guidance. Dietary therapy for these patients may have the potential to improve kidney graft function and survival.
建议限制蛋白质、盐和能量的摄入，以预防肾移植患者的生活方式相关疾病、蛋白尿和移植肾功能障碍。如果患者能够自行评估每餐的膳食成分，将会很有帮助。
本研究共纳入26例维持期肾移植患者。在病历上记录患者的平均年龄、性别、体重指数、移植后年限、肌酐清除率以及24小时尿蛋白排泄量（24 UE）。分别根据氮和钠的24 UE计算每日估计蛋白质和盐的口服摄入量。我们使用基于智能手机的食谱营养计算器（SRNC）比较了这些实验室结果与患者自我报告的饮食摄入量。
根据氮和钠的24 UE计算出的每日估计蛋白质和盐的口服摄入量分别为55.4±12.9 g/天和8.5±3.1 g/天。通过SRNC测量的每日估计蛋白质和盐的口服摄入量分别为52.4±13.8 g/天和6.5±0.9 g/天。通过SRNC测量的每日估计蛋白质和盐的口服摄入量结果与根据24 UE计算的结果相关（R分别为0.287和0.217）。
在维持期肾移植患者中，通过SRNC测量的每日估计蛋白质和盐的口服摄入量结果与根据24 UE计算的结果相关。SRNC作为一种评估饮食指导依从性的测量方式很有用。对这些患者的饮食治疗可能有改善肾移植功能和存活率的潜力。
