Department of Woman's and Child's Health - University Hospital of Padova, Padova, Italy.
Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
J Pediatr. 2019 Aug;211:215-218. doi: 10.1016/j.jpeds.2019.04.006. Epub 2019 May 7.
Long-term survivors of bronchopulmonary dysplasia develop chronic obstructive lung disease. Herein we report in vivo histopathology from bronchial biopsies of 3 adolescent survivors of severe bronchopulmonary dysplasia. Thickened basement membranes with lymphocytic infiltrates and signs of immature neoangiogenesis in the absence of T-helper lymphocytes or eosinophils suggest the presence of an ongoing active airway process.
支气管肺发育不良的长期幸存者会发展为慢性阻塞性肺病。在此，我们报告了 3 例严重支气管肺发育不良青少年幸存者的支气管活检的体内组织病理学。增厚的基底膜伴有淋巴细胞浸润，并出现不成熟的新生血管形成迹象，但缺乏辅助性 T 淋巴细胞或嗜酸性粒细胞，提示存在持续的气道活跃过程。
