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神经元证据表明,在识别记忆的某些潜在过程中,颞叶内下皮质比海马体更重要。

Neuronal evidence that inferomedial temporal cortex is more important than hippocampus in certain processes underlying recognition memory.

作者信息

Brown M W, Wilson F A, Riches I P

出版信息

Brain Res. 1987 Apr 14;409(1):158-62. doi: 10.1016/0006-8993(87)90753-0.

DOI:10.1016/0006-8993(87)90753-0
PMID:3107754
Abstract

Amnesia has been reported to result from combined damage to the amygdala, hippocampus and inferomedial temporal cortex in man and monkey. Evidence is presented that neuronal activity in the monkey inferomedial temporal cortex reflects memory for the previous occurrence of visual stimuli: 26 (15%) of 173 single units responded more strongly to first than to subsequent presentations of unfamiliar stimuli. No such responses were found for neurones recorded in the hippocampus and subicular cortex. The findings suggest that the inferomedial temporal cortex plays a central role in processes necessary for recognition memory.

摘要

据报道,人类和猴子的杏仁核、海马体以及颞叶内下皮质联合受损会导致失忆。有证据表明,猴子颞叶内下皮质的神经元活动反映了对先前视觉刺激出现的记忆:在173个单个神经元中,有26个(15%)对首次呈现的陌生刺激的反应比对后续呈现的反应更强烈。在海马体和海马下皮质记录的神经元未发现此类反应。这些发现表明,颞叶内下皮质在识别记忆所需的过程中起核心作用。

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