产 ESBL 大肠杆菌在爱尔兰和荷兰养老院居民中的传播可能反映了基础设施的差异。
Spread of ESBL-producing Escherichia coli in nursing home residents in Ireland and the Netherlands may reflect infrastructural differences.
机构信息
Department of Medical Microbiology, Leiden University Medical Centre, Leiden, the Netherlands.
Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin, Ireland.
出版信息
J Hosp Infect. 2019 Oct;103(2):160-164. doi: 10.1016/j.jhin.2019.05.003. Epub 2019 May 9.
A prevalence study in two nursing homes (one each in the Netherlands and Ireland) found four (11%) Dutch and six (9%) Irish residents colonized with 11 extended-spectrum beta-lactamase-producing Escherichia coli, 10 of which contained CTX-M-15. Four Dutch isolates, from three residents of the same ward, belonged to E. coli O25:H4, sequence type (ST) 131 and were part of the same cluster type by whole-genome sequencing. Four Irish residents on three different wards were colonized with an identical E. coli O89:H9, ST131, complex type 1478. Cross-transmission between three Irish wards may reflect differences in nursing home infrastructure, specifically communal areas and multi-bedded resident rooms.
一项在两家养老院（一家在荷兰，一家在爱尔兰）进行的流行性病学研究发现，4 名（11%）荷兰居民和 6 名（9%）爱尔兰居民定植了 11 株产超广谱β-内酰胺酶的大肠埃希菌，其中 10 株含有 CTX-M-15。4 株来自同一病房的 3 名居民的荷兰分离株属于大肠埃希菌 O25：H4、序列型（ST）131，通过全基因组测序属于同一聚类型。3 个不同病房的 4 名爱尔兰居民定植了一株相同的大肠埃希菌 O89：H9、ST131、复合型 1478。3 名爱尔兰居民之间的交叉传播可能反映了养老院基础设施的差异，特别是公共区域和多床位居民房间。
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