Research Center for Child Mental Development, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8640, Japan.
Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
J Autism Dev Disord. 2019 Aug;49(8):3462-3469. doi: 10.1007/s10803-019-04053-6.
Olfactory adaptation is an important process that allows the individual to adjust to changes in the environment. This process has been proposed to be aberrant in individuals with autism spectrum disorders (ASD). However, few studies have examined olfactory adaptation in children with ASD. We examined olfactory adaptation in children with ASD and typically developing (TD) children using a pulse ejection system, which resolved problems associated with previous laboratory-based olfactory psychophysical studies. Nine children with ASD and nine TD children participated in this study and all participants completed the entire experiment. Using this system, we found that the TD group showed greater adaptation than the ASD group. Our results provide a better understanding of olfactory adaptation in children with ASD.
嗅觉适应是一种重要的过程,使个体能够适应环境的变化。有人提出,自闭症谱系障碍(ASD)个体的这一过程存在异常。然而,很少有研究检查过 ASD 儿童的嗅觉适应。我们使用脉冲喷射系统检查了 ASD 儿童和典型发育(TD)儿童的嗅觉适应,该系统解决了之前基于实验室的嗅觉心理物理学研究中存在的问题。9 名 ASD 儿童和 9 名 TD 儿童参加了这项研究,所有参与者都完成了整个实验。使用该系统,我们发现 TD 组的适应能力强于 ASD 组。我们的研究结果更好地理解了 ASD 儿童的嗅觉适应。