基层医疗中检测外周动脉疾病：一项基于人群的研究。

Detecting Peripheral Arterial Disease in Primary Care: A Population Based Study.

作者信息

Vural Tolga, Tan Makbule Neslişah, Kartal Mehtap, Güldal Azize Dilek

机构信息

Incirliova Family Health Center, Aydın, Turkey.

Department of Family Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey.

出版信息

Korean J Fam Med. 2020 Jan;41(1):61-67. doi: 10.4082/kjfm.18.0066. Epub 2019 May 13.

DOI:10.4082/kjfm.18.0066

PMID:31079441

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6987029/

Abstract

BACKGROUND

Peripheral arterial disease (PAD) can progress silently without any clinical symptoms. Ankle-brachial index (ABI) is the recommended method used in primary care. We aimed to determine the prevalence of PAD and its related risk factors in primary care.

METHODS

In this cross-sectional study, 250 participants aged ≥45 years were recruited randomly from the registered patients of family health center in a district of Izmir, Turkey. Patients' demographic data, PAD symptoms, and PAD risk factors were obtained. The PAD group consisted of patients with ABI levels <0.9; the non-compressible artery (NCA) group consisted of patients with ABI levels >1.3.

RESULTS

The prevalence of PAD was 17.6% (22.5% in women and 11.1% in men), while that of NCA was 15.2% (12.7% in women and 25.0% in men). About 27.3% and 54.5% of patients with PAD did not have claudication and problems with walking distance, respectively. Of the NCA patients, 15.8% had problems with walking distance and 39.5% had claudication. Regression analysis revealed two predictors of PAD (age ≥65 years: odds ratio [OR], 3.51; 95% confidence interval [CI], 1.65-7.47; claudication: OR, 3.41; 95% CI, 1.58-7.39) and three predictors of NCA (age <65 years: OR, 2.55; 95% CI, 1.01-6.45; male sex: OR, 2.40; 95% CI, 1.10-5.25; triglyceride [TG] >200 mg/dL: OR, 4.11; 95% CI, 1.58-10.67).

CONCLUSION

PAD had a prevalence of 17.6% and was associated with age ≥65 years and claudication. NCA had a prevalence of 15.2% and was associated with age <65 years, TG >200 mg/dL, and male sex.

摘要

背景

外周动脉疾病（PAD）可在无任何临床症状的情况下悄然进展。踝臂指数（ABI）是初级保健中推荐使用的方法。我们旨在确定初级保健中PAD的患病率及其相关危险因素。

方法

在这项横断面研究中，从土耳其伊兹密尔一个区的家庭健康中心登记患者中随机招募了250名年龄≥45岁的参与者。获取了患者的人口统计学数据、PAD症状和PAD危险因素。PAD组由ABI水平<0.9的患者组成；不可压缩动脉（NCA）组由ABI水平>1.3的患者组成。

结果

PAD的患病率为17.6%（女性为22.5%，男性为11.1%），而NCA的患病率为15.2%（女性为12.7%，男性为25.0%）。分别约有27.3%和54.5%的PAD患者没有间歇性跛行和步行距离问题。在NCA患者中，15.8%有步行距离问题，39.5%有间歇性跛行。回归分析揭示了PAD的两个预测因素（年龄≥65岁：比值比[OR]为3.51；95%置信区间[CI]为1.65 - 7.47；间歇性跛行：OR为3.41；95% CI为1.58 - 7.39）以及NCA的三个预测因素（年龄<65岁：OR为2.55；95% CI为1.01 - 6.45；男性：OR为2.40；95% CI为1.10 - 5.25；甘油三酯[TG]>200 mg/dL：OR为4.11；95% CI为1.58 - 10.67）。