Heart, Lung and Blood Vessel Center, Tongji University School of Medicine, Shanghai, China.
Vasc Med. 2010 Oct;15(5):361-9. doi: 10.1177/1358863X10378376.
The ankle-brachial index (ABI) is a simple, inexpensive diagnostic test for peripheral artery disease (PAD). However, it has shown variable accuracy for identification of significant stenosis. The authors performed a structured review of the sensitivity and specificity of ABI ≤ 0.90 for the diagnosis of PAD. MEDLINE, EMBASE, Cochrane databases, Science Citation Index database, and Biological Abstracts database were searched for studies of the sensitivity and specificity of using ABI ≤ 0.90 for the diagnosis of PAD. Eight studies comprising 2043 patients (or limbs) met the inclusion criteria. The result indicated that, although strict inclusion criteria on studies were formulated, different reference standards were found in these studies, and methods of ABI determination and characteristics of populations varied greatly. A high level of specificity (83.3-99.0%) and accuracy (72.1-89.2%) was reported for an ABI ≤ 0.90 in detecting ≥ 50% stenosis, but there were different levels of sensitivity (15-79%). Sensitivity was low, especially in elderly individuals and patients with diabetes. In conclusion, the test of ABI ≤ 0.90 can be a simple and useful tool to identify PAD with serious stenosis, and may be substituted for other non-invasive tests in clinical practice.
踝臂指数（ABI）是一种用于诊断外周动脉疾病（PAD）的简单、廉价的诊断测试。然而，它在识别严重狭窄方面的准确性存在差异。作者对 ABI≤0.90 用于诊断 PAD 的敏感性和特异性进行了系统评价。在 MEDLINE、EMBASE、Cochrane 数据库、科学引文索引数据库和生物学文摘数据库中搜索了用于诊断 PAD 的 ABI≤0.90 的敏感性和特异性的研究。有 8 项研究共纳入 2043 例患者（或肢体）符合纳入标准。结果表明，尽管对研究制定了严格的纳入标准，但这些研究中发现了不同的参考标准，ABI 测定方法和人群特征差异很大。ABI≤0.90 检测≥50%狭窄的特异性（83.3-99.0%）和准确性（72.1-89.2%）较高，但敏感性不同（15-79%）。敏感性较低，尤其是在老年患者和糖尿病患者中。总之，ABI≤0.90 检测可作为一种简单、有用的工具，用于识别严重狭窄的 PAD，可替代临床实践中的其他非侵入性检查。
