Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Charlotte Bloomberg Children's Hospital, Baltimore, MD, USA.
Department of Surgery, Johns Hopkins School of Medicine, Johns Hopkins Children's Center, Charlotte Bloomberg Children's Hospital, Baltimore, MD, USA.
J Pediatr Surg. 2019 Nov;54(11):2408-2412. doi: 10.1016/j.jpedsurg.2019.03.022. Epub 2019 Apr 26.
Due to the large abdominal defect from the omphalocele and extreme pubic diastasis in cloacal exstrophy (CE), bioprosthetic material may be used to bridge this gap during abdominal closure in CE. This study examined presurgical factors associated with the use of bioprosthetic materials in CE closure and complications in these patients.
An institutional database of exstrophy-epispadias complex patients was reviewed for CE. Inclusion criteria included CE and primary closure performed at the host institution from 1998 to 2018. Data collection included demographics, presurgical factors, use of bioprosthetic material, complications, and outcomes.
All 32 patients had a staged closure and pelvic osteotomy prior to bladder closure. Ten of the 32 patients incorporated a bioprosthetic material during abdominal wall closure. There is at least 3 months follow up for all patients, all had successful bladder closure without any postoperative hernias. Those who underwent closure without bioprosthetic material were younger at the time of closure (565 vs 693 days, p = 0.043). The differences in complication rates and mean pubic diastasis was not statistically significant, p = 0.079 and p = 0.457 respectively.
The use of bioprosthetic material is associated with older age at abdominal wall and bladder closure. The use of bioprosthetic material is a useful adjunct for secure abdominal wall closure in the reconstruction of CE.
Prognostic.
III.
由于脐膨出和直肠外生殖器裂(CE)的巨大腹部缺陷以及耻骨分离,在 CE 腹壁关闭时可能使用生物假体材料来桥接这个间隙。本研究检查了与 CE 闭合中使用生物假体材料相关的术前因素以及这些患者的并发症。
回顾了一个外生殖器裂-尿道上裂复合畸形患者的机构数据库,以寻找 CE 患者。纳入标准包括在本机构进行的 CE 和一期修复,时间为 1998 年至 2018 年。数据收集包括人口统计学资料、术前因素、生物假体材料的使用、并发症和结果。
所有 32 例患者均接受了分期修复和骨盆截骨术,然后再进行膀胱闭合。32 例患者中有 10 例在腹壁关闭时采用了生物假体材料。所有患者均至少随访 3 个月,所有患者均成功地完成了膀胱闭合,且术后无疝。未使用生物假体材料进行闭合的患者在闭合时年龄较小(565 天 vs 693 天,p=0.043)。并发症发生率和平均耻骨分离的差异无统计学意义,p=0.079 和 p=0.457。
生物假体材料的使用与腹壁和膀胱闭合时的年龄较大有关。生物假体材料的使用是 CE 重建中安全腹壁闭合的有用辅助手段。
预后。
III。