Department of General Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Med Sci Monit. 2019 May 13;25:3537-3541. doi: 10.12659/MSM.916475.
d_abstr_R Gastric cancer is a common malignancy with a poor prognosis, and surgical treatment remains the first-line approach to treatment to provide a cure. Despite advances in surgical techniques, radiotherapy, chemotherapy, and neoadjuvant therapy, gastric cancer remains the second leading cause of cancer death worldwide. Although the 5-year survival rate of early gastric cancer can reach >90%, due to the low early diagnosis rate, most patients present with advanced-stage gastric cancer. Therefore, there has been increasing interest in improving surgical treatment of advanced gastric cancer. Lymph node dissection is an important part of the surgical treatment of advanced gastric cancer due to the high incidence of lymph node metastasis. Although prospective studies have confirmed the safety and feasibility of laparoscopic surgery for early gastric cancer, the relevant treatment models of advanced gastric cancer still need to be further explored and validated. This review aims to provide an update on the recent advances in the surgical treatment of advanced gastric cancer.
胃癌是一种预后较差的常见恶性肿瘤,手术治疗仍然是治疗的首选方法,可提供治愈机会。尽管手术技术、放疗、化疗和新辅助治疗有所进展,但胃癌仍然是全球癌症死亡的第二大主要原因。尽管早期胃癌的 5 年生存率可达到>90%,但由于早期诊断率低,大多数患者就诊时已处于晚期胃癌。因此,人们越来越关注改善晚期胃癌的手术治疗。由于淋巴结转移发生率高,淋巴结清扫是晚期胃癌手术治疗的重要组成部分。尽管前瞻性研究已经证实了腹腔镜手术治疗早期胃癌的安全性和可行性,但晚期胃癌的相关治疗模式仍需要进一步探索和验证。本综述旨在提供晚期胃癌手术治疗的最新进展。