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Exophilin-5 Supports Lysosome-Mediated Trafficking Required for Epidermal Differentiation.

作者信息

Monteleon Christine L, Lee In Young, Ridky Todd W

机构信息

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

J Invest Dermatol. 2019 Oct;139(10):2219-2222.e6. doi: 10.1016/j.jid.2019.04.014. Epub 2019 May 11.

Abstract
摘要

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Lysosomes Support the Degradation, Signaling, and Mitochondrial Metabolism Necessary for Human Epidermal Differentiation.
J Invest Dermatol. 2018 Sep;138(9):1945-1954. doi: 10.1016/j.jid.2018.02.035. Epub 2018 Mar 9.
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Association of Epidermolysis Bullosa Simplex With Mottled Pigmentation and EXPH5 Mutations.
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Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis.
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Lysosomal exocytosis and caspase-8-mediated apoptosis in UVA-irradiated keratinocytes.
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Molecular heterogeneity of epidermolysis bullosa simplex: contribution of EXPH5 mutations.
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Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility.
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