Matsuoka R, Mori H, Tomonari R, Chen S Z, Kigawa T, Aisaka K
Nihon Sanka Fujinka Gakkai Zasshi. 1987 Apr;39(4):586-90.
To clarify the diagnostic criteria of occulted or transient hyperprolactinemia, the resting prolactin level and the prolactin secreting capacity of normal women, which were tested with a 500 micrograms of TRH injection, were compared with those of patients with occulted hyperprolactinemia. Results revealed that: resting levels of prolactin in normal women were 13.4 +/- 4.4 ng/ml (mean +/- S.D.) in the follicular phase and 13.4 +/- 5.6 ng/ml in the luteal phase, which overlapped those of occulted hyperprolactinemia. the prolactin secreting capacity of occulted hyperprolactinemia was significantly greater than that of the normal women. These results indicated that it was impossible to distinguish the occulted hyperprolactinemia from the normal by the measuring the resting prolactin level, but possible by the evaluating the prolactin secreting capacity. If the serum prolactin was more than 150 ng/ml at 15 min. after TRH administration, occulted hyperprolactinemia was strongly suggested.
为明确隐匿性或短暂性高催乳素血症的诊断标准，将500微克促甲状腺激素释放激素（TRH）注射后检测的正常女性静息催乳素水平及催乳素分泌能力，与隐匿性高催乳素血症患者的相应指标进行比较。结果显示：正常女性在卵泡期的静息催乳素水平为13.4±4.4纳克/毫升（均值±标准差），黄体期为13.4±5.6纳克/毫升，与隐匿性高催乳素血症患者的水平有重叠。隐匿性高催乳素血症的催乳素分泌能力显著高于正常女性。这些结果表明，通过测量静息催乳素水平无法区分隐匿性高催乳素血症与正常情况，但通过评估催乳素分泌能力则有可能区分。若TRH给药后15分钟血清催乳素超过150纳克/毫升，则强烈提示隐匿性高催乳素血症。
