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带自体骨移植的交锁髓内钉治疗股骨干骨折无菌性骨不连的疗效评估

Evaluation of Outcome of Exchange Nailing with Autogenous Bone Graft for Treating Aseptic Nonunion of Femoral Shaft Fracture.

作者信息

Alam Q S, Alam M T, Reza M S, Roy M K, Kamruzzaman M, Sayed K A, Alamgir M K, Mohiuddin A M

机构信息

Dr Quazi Shahid-Ul Alam, Registrar (Paediatric Orthopaedics), Department of Orthopaedic Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2019 Apr;28(2):378-381.

Abstract

Femoral shaft fractures are severe injuries and challenging for both, the patient and the surgeon. This study has been designed to assess the success rate of exchange nailing with autogenous cancellous bone graft for the treatment of non united femoral shaft fractures previously treated by ORIF with intramedullary nail. This quasi experimental study was carried out in the Department of Orthopaedics & Traumatology of Dhaka Medical College Hospital and NITOR from July 2007 to December 2008. Thirteen patients were followed up regularly for at least 1 (one) year after each operation to assess the functional outcome as well as union time according to the prescribed scoring system. Final outcome was analyzed by SPSS-18 version. Level of significance was set at 0.05 (p<0.05). In this study exchange nailing with autogenous cancellous bone graft were done for femoral shaft fracture with nonunion in 13 patients. Mean±SD age was 39.08±5.780 years; Male: Female = 9:4. Among 13 nonunion fractures, all (100%) were united after exchange nailing with autogenous cancellous bone graft in aseptic condition. Mean union time was 26.97±2.976 weeks in static mode of fixation. Union time was highest in atrophic type of fracture and lowest in hypertrophic type of fracture. Final outcome according to modified Thoresen's score was satisfactory 92.29%; according to modified Silvia's score was 10.77±0.832. Exchange nailing with autogenous cancellous bone graft is an effective method of treatment in femoral shaft fracture with nonunion after intramedullary nailing. It provides a good scope to reinforce the optimum mechanical stability by a larger diameter nail and locked if necessary; as well as biological stimulation by reaming and bone grafting.

摘要

股骨干骨折是严重损伤,对患者和外科医生来说都是挑战。本研究旨在评估自体松质骨移植交锁髓内钉治疗先前采用切开复位髓内钉固定术后股骨干骨折不愈合的成功率。这项准实验研究于2007年7月至2008年12月在达卡医学院医院骨科与创伤科及NITOR开展。13例患者在每次手术后均接受至少1年的定期随访,以根据规定的评分系统评估功能结果及愈合时间。最终结果采用SPSS 18版进行分析。显著性水平设定为0.05(p<0.05)。本研究中,对13例股骨干骨折不愈合患者采用自体松质骨移植交锁髓内钉治疗。平均年龄±标准差为39.08±5.780岁;男女比例为9:4。在13例骨折不愈合病例中,所有(100%)在无菌条件下采用自体松质骨移植交锁髓内钉治疗后均实现愈合。静态固定模式下的平均愈合时间为26.97±2.976周。萎缩型骨折的愈合时间最长,肥大型骨折的愈合时间最短。根据改良的托勒森评分,最终结果令人满意的比例为92.29%;根据改良的西尔维亚评分,评分为10.77±0.832。自体松质骨移植交锁髓内钉是治疗髓内钉固定术后股骨干骨折不愈合的有效方法。它为通过使用更大直径的髓内钉并在必要时锁定来增强最佳机械稳定性提供了良好的条件;同时通过扩髓和植骨提供生物刺激。

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