Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Mein Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Division of Neurology, Department of Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Nat Rev Neurol. 2019 Aug;15(8):441-445. doi: 10.1038/s41582-019-0194-0.
The latest revision of the McDonald criteria for the diagnosis of multiple sclerosis (MS) was published online in 2017. New features of the criteria, which were designed to facilitate earlier diagnosis of MS, include the recognition of oligoclonal bands in the cerebrospinal fluid as a possible marker of dissemination of MS pathology in time, the introduction of symptomatic lesions as a parameter to demonstrate spatial or temporal pathology dissemination, and the use of cortical lesions to demonstrate dissemination in space. In this Viewpoint, a panel of world-renowned MS specialists share their personal experiences of the new criteria to date.
2017 年，多发性硬化症（MS）诊断的麦当劳标准的最新修订版在线发布。这些标准的新特点旨在促进 MS 的早期诊断，包括将脑脊液中的寡克隆带识别为 MS 病理学在时间上传播的可能标志物，将症状性病变引入作为证明空间或时间病理学传播的参数，以及使用皮质病变来证明空间传播。在本观点中，一组世界著名的多发性硬化症专家分享了他们迄今为止对新标准的个人经验。
