Tehran University of Medical Sciences, Tehran, Iran.
Breast Disease Research Centre, TUMS, Tehran, Iran.
Breast J. 2019 Jul;25(4):672-677. doi: 10.1111/tbj.13300. Epub 2019 May 13.
The goal of this study is to compare the response rate and the recurrence rate of available therapeutic modalities in the treatment of Idiopathic Granulomatous Mastitis (IGM). 374 patients with pathologically confirmed IGM, were included. They were subdivided into three levels of severity. Close observation had the best response rate with the lowest recurrence rate in mild to moderate cases. Severe cases were mostly treated by prednisolone or underwent surgery. The outcome of prednisolone use in severe cases was comparable to NSAIDs. Overall 9% were resistant to treatment and surgical intervention is still an option among them.
本研究旨在比较特发性肉芽肿性乳腺炎（IGM）各种治疗方法的应答率和复发率。共纳入 374 例经病理证实的 IGM 患者，将其分为 3 个严重程度级别。在轻中度病例中，密切观察的应答率最高，复发率最低。严重病例大多采用泼尼松龙治疗或手术治疗。严重病例中泼尼松龙的使用效果与 NSAIDs 相当。总体而言，有 9%的患者对治疗无反应，手术干预仍然是其中一种选择。
