α1-抗胰蛋白酶与炎症性牙周病的关系。
The relationship of alpha1-antitrypsin to inflammatory periodontal disease.
作者信息
Peterson R J, Marsh C L
出版信息
J Periodontol. 1979 Jan;50(1):31-5. doi: 10.1902/jop.1979.50.1.31.
PMID:310876
Abstract
Alpha1-antitrypsin (alpha1-AT) is a serum protease inhibitor with a well established role in bodily defense against destructive inflammatory diseases. alpha1-AT exhibits inheritable genetic polymorphism (Pi types). Certain Pi types have been shown to predispose to emphysema and, in this study, also appear to be related to increased chronic periodontitis susceptibility.
摘要
α1-抗胰蛋白酶（α1-AT）是一种血清蛋白酶抑制剂，在机体抵御破坏性炎症性疾病的防御中发挥着既定作用。α1-AT表现出可遗传的基因多态性（Pi型）。某些Pi型已被证明易患肺气肿，并且在本研究中，似乎也与慢性牙周炎易感性增加有关。
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