Department of Public Health and Policy, Farr Institute, University of Liverpool, Liverpool, L69 3GB, UK.
University College London Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK.
BMC Pediatr. 2019 May 15;19(1):150. doi: 10.1186/s12887-019-1514-7.
Childhood unintentional injuries (UI) are common but continue to happen more often to children living in less advantaged socioeconomic circumstances (SEC). Our aim was to explore how early life factors mediate the association between SEC and UIs, using the UK Millennium Cohort Study.
We calculated risk ratios (RR) and 95% confidence intervals (95%CI) for parental report of UI occurring between age 3 and 5 years, using Poisson regression according to family income as a measure of SEC. We explored potentially mediating pathways by controlling associations between SEC and UI for groups of early life risks in three domains: factors that may influence environmental safety, supervision and the MCS child's abilities and behaviours.
Twenty eight percent of children had a UI from 3 to 5 years old. Children from the lowest income quintile were more likely to be injured compared to those from the highest (RR 1.20 95%CI 1.05, 1.37). Sequentially controlling for early life factors that may influence environmental safety (RR 1.19 95%CI 1.02, 1.38), then supervision (RR 1.18, 95%CI 1.02, 1.36), and finally adding child's behaviour and abilities (RR 1.15, 95%CI 1.00, 1.34) into the model reduced the RR by 5, 10 and 25% respectively.
Addressing factors that may influence environmental safety and supervision, and the child's abilities and behaviours only partly explains the increased UI risk between the highest and lowest income quintiles. Further research is required to explore factors mediating associations between SEC and specific mechanisms and types of injuries.
儿童意外伤害(UI)很常见,但生活在社会经济地位较低的儿童中仍经常发生。我们的目的是利用英国千禧年队列研究探索早期生活因素如何调节社会经济地位与 UI 之间的关系。
我们根据家庭收入来衡量社会经济地位,使用泊松回归计算了 3 至 5 岁期间父母报告的 UI 发生率的风险比(RR)和 95%置信区间(95%CI)。我们通过控制三个领域的早期生活风险组之间的 SEC 和 UI 之间的关联,探索了潜在的中介途径:可能影响环境安全、监督以及 MCS 儿童能力和行为的因素。
28%的儿童在 3 至 5 岁之间发生了 UI。与来自最高收入五分位数的儿童相比,来自最低收入五分位数的儿童受伤的可能性更高(RR 1.20,95%CI 1.05,1.37)。依次控制可能影响环境安全的早期生活因素(RR 1.19,95%CI 1.02,1.38)、监督(RR 1.18,95%CI 1.02,1.36),最后将儿童的行为和能力(RR 1.15,95%CI 1.00,1.34)添加到模型中,RR 分别降低了 5%、10%和 25%。
解决可能影响环境安全和监督以及儿童能力和行为的因素,仅部分解释了最高和最低收入五分位数之间 UI 风险增加的原因。需要进一步研究来探索调节社会经济地位与特定机制和类型伤害之间关联的因素。