Barkhatova A N
Mental Health Research Centre, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(3):5-11. doi: 10.17116/jnevro20191190315.
To identify main clinical and psychopathological models of remission in the initial stage of schizophrenia which were correlated with subsequent clinical and social prognosis.
The sample consisted of 116 patients diagnosed with paroxysmal-progressive schizophrenia (ICD-10 items F20.01-F20.09) in remission after the first or second episode. Clinical-psychopathological, psychometric (SPI-A), statistical methods were used. The separation of remissions in the initial stage of schizophrenia was based on the principle of longitudinal observation with estimation of correlations between deficit disorders and positive symptoms.
Depending on the predominance of one of the factors of the deficit symptom complex, the following modules were identified: remissions with domination of deficit expression factor and remissions with deficit apathy factor, which were correlated with the clinical and social prognosis.
确定精神分裂症初始阶段缓解的主要临床和精神病理学模式,这些模式与后续的临床和社会预后相关。
样本包括116例在首次或第二次发作后处于缓解期的阵发性进行性精神分裂症(ICD - 10编码F20.01 - F20.09)患者。采用临床精神病理学、心理测量学(SPI - A)和统计学方法。精神分裂症初始阶段缓解的分类基于纵向观察原则,评估缺陷障碍与阳性症状之间的相关性。
根据缺陷症状复合体中一个因素的优势,确定了以下模块:以缺陷表达因素为主导的缓解和以缺陷性冷漠因素为主导的缓解,它们与临床和社会预后相关。