School of Chemistry and Materials Science, Jiangsu Key Lab of Green Synthetic Chemistry for Functional Materials. Jiangsu Normal University, Xuzhou, Jiangsu 221116, P R China.
Org Biomol Chem. 2019 May 29;17(21):5283-5293. doi: 10.1039/c9ob00194h.
A regiodivergent allylation of N-acylhydrazones with Morita-Baylis-Hillman (MBH) carbonates has been developed, providing α- or γ-allylated products in excellent yields by using different catalysts. The nature of the base catalyst plays a pivotal role in controlling the reaction pathway, allowing regiospecific access to diverse allylic substituted target compounds from identical substrates.
发展了 N-酰腙与 Morita-Baylis-Hillman (MBH) 碳酸酯的区域发散性烯丙基化反应，使用不同的催化剂可高产率得到 α-或 γ-烯丙基化产物。碱催化剂的性质在控制反应途径方面起着关键作用，允许从相同的底物中以区域选择性方式获得不同的烯丙基取代的目标化合物。
