Vargas Sandra Lucía, Céspedes Diana Carolina, Vergel Juan David, Ruiz Erika Paola, Luna María Camila
Facultad de Medicina, Universidad El Bosque, Bogotá, Colombia.
Rev Chilena Infectol. 2018;35(6):658-668. doi: 10.4067/S0716-10182018000600658.
Dengue and chikungunya viruses are transmitted by the female Aedes aegypti and Aedes albopictus, which are widely distributed in tropical and subtropical areas, facilitating coinfection.
To determine the magnitude, geographical distribution and clinical picture of dengue and chikungunya coinfection.
Narrative review. A search in the PubMed and Lilacs databases was made, using the MeSH terms "Chikungunya", "CHIKV", "DENV", "Dengue" and "coinfection. The articles of the last 20 years were included.
A total of 45 articles were included. The largest coinfection report was in Asia followed by Africa. In the Americas, the information is limited because of the recent circulation of chikungunya. The magnitude of coinfection varies between 0% and 31.9%. No differences were found in the distribution of coinfection by sex and age. The clinical picture of monoinfection and coinfection was similar. Some case reports show severe cases with central nervous system involvement, hemorrhagic manifestations and Still's disease.
The clinical manifestations of coinfection by dengue and chikungunya viruses are similar to those due to monoinfection, which difficult the diagnosis and measurement of its magnitude.
登革热病毒和基孔肯雅病毒由埃及伊蚊和白纹伊蚊的雌性传播，这两种蚊子广泛分布于热带和亚热带地区，易造成共同感染。
确定登革热和基孔肯雅病毒共同感染的规模、地理分布及临床表现。
叙述性综述。在PubMed和Lilacs数据库中进行检索，使用医学主题词“基孔肯雅热”“基孔肯雅病毒”“登革病毒”“登革热”和“共同感染”。纳入过去20年的文章。
共纳入45篇文章。共同感染报告最多的是亚洲，其次是非洲。在美洲，由于基孔肯雅热近期才开始传播，相关信息有限。共同感染的规模在0%至31.9%之间变化。未发现共同感染在性别和年龄分布上存在差异。单一感染和共同感染的临床表现相似。一些病例报告显示存在累及中枢神经系统、出血表现和斯蒂尔病的严重病例。
登革热病毒和基孔肯雅病毒共同感染的临床表现与单一感染相似，这使得其诊断和规模测定变得困难。
