Lunsford L Dade, Niranjan Ajay, Flickinger John C
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA,
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Prog Neurol Surg. 2019;34:9-18. doi: 10.1159/000493045. Epub 2019 May 16.
A decision to develop a stereotactic radiosurgery center and install the first 201 cobalt-60 Gamma Knife in Pittsburgh was made in 1981 after gathering regional and leadership support. This was part of a 7-year quest that required overcoming barriers to a new technology unfamiliar to US regulatory authorities and insurance companies. The first patient was treated in August 1987. Since that time our center has installed each succeeding Gamma Knife device developed. During an initial 30-year experience we performed more than 14,750 patient procedures. In addition to patient care our Center's goal was to develop a major teaching and clinical research program that eventually led to the training of more than 2,500 physicians and medical physicists, the publication of more than 600 peer-reviewed clinical outcome research studies, and 4 books. This report summarizes the rationale for acquisition, the challenges and the early years, and then the evolution of our center which installed the first US 201 source Gamma Knife.
1981年，在获得地区和领导层支持后，决定在匹兹堡建立一个立体定向放射外科中心并安装第一台201钴 - 60伽玛刀。这是一项为期7年的探索的一部分，期间需要克服美国监管机构和保险公司对这项新技术不熟悉所带来的障碍。首例患者于1987年8月接受治疗。从那时起，我们中心安装了后续研发的每一款伽玛刀设备。在最初的30年经验中，我们实施了超过14,750例患者手术。除了患者护理，我们中心的目标是开展一项重要的教学和临床研究项目，最终培养了2500多名医生和医学物理学家，发表了600多篇同行评审的临床结果研究报告，并出版了4本书籍。本报告总结了购置的理由、面临的挑战和早期情况，以及我们安装美国第一台201源伽玛刀的中心的发展历程。
