Kano Hideyuki, Niranjan Ajay, Lunsford L Dade
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA,
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Prog Neurol Surg. 2019;34:207-214. doi: 10.1159/000493066. Epub 2019 May 16.
Chordomas and chondrosarcomas are rare locally aggressive skull base tumors with high progression or recurrence rates. Ultimately, they have high mortality rates unless they respond to multimodality management options that include one or more surgical resections, fractionated radiation therapy, and stereotactic radiosurgery (SRS). SRS has become a standard management option for recurrent or residual chordomas and chondrosarcomas after failed surgical resection and fractionated radiation therapy. This report examines the role of SRS in these skull base tumors.
脊索瘤和软骨肉瘤是罕见的局部侵袭性颅底肿瘤，具有较高的进展或复发率。最终，除非它们对包括一次或多次手术切除、分次放射治疗和立体定向放射外科（SRS）在内的多模式治疗方案有反应，否则死亡率很高。SRS已成为手术切除和分次放射治疗失败后复发性或残留性脊索瘤和软骨肉瘤的标准治疗选择。本报告探讨了SRS在这些颅底肿瘤中的作用。
