Zhao Lei, Lin Ying, Jiang Tingting, Wang Ling, Li Min, Wang Ying, Sun Guoqiang, Xiao Mei
Department of Obstetrics, Maternity and Child Health Hospital of Hubei Province, Hongshan District, Wuhan, China.
J Int Med Res. 2019 Jun;47(6):2647-2654. doi: 10.1177/0300060519845780. Epub 2019 May 17.
This study aimed to investigate the potential factors that affect the induction to delivery time interval in women undergoing induction of labor with a controlled-release dinoprostone vaginal insert.
Pregnant women who presented for delivery at Hubei Maternal and Child Health Hospital from January 2016 to August 2016 were recruited. Finally, 1265 women who underwent labor induction with a vaginal dinoprostone (PGE2) insert were analyzed. Univariate and multivariate linear regression analyses were used to estimate the relevant risks for delivery time.
Among the1265 subjects, the mean delivery time was 18.92 ± 12.50 hours. Univariate and multivariate analyses showed that fetal weight, an obstetric complication (premature rupture of the membranes), and the delivery history were significantly associated with the induction to delivery time. Biparietal diameter was related to the vaginal delivery time in univariate analysis, but there was no significant difference after adjustment in multivariate analysis.
Vaginal dinoprostone is an effective method for successful induction of labor. Gestational age, parity, and fetal weight are major factors that predict the induction to delivery time interval.
本研究旨在探讨使用控释地诺前列酮阴道栓剂引产的女性中，影响引产至分娩时间间隔的潜在因素。
招募2016年1月至2016年8月在湖北省妇幼保健院就诊分娩的孕妇。最终，对1265例使用阴道地诺前列酮（PGE2）栓剂引产的女性进行了分析。采用单因素和多因素线性回归分析来评估分娩时间的相关风险。
在1265名受试者中，平均分娩时间为18.92±12.50小时。单因素和多因素分析表明，胎儿体重、产科并发症（胎膜早破）和分娩史与引产至分娩时间显著相关。单因素分析中双顶径与阴道分娩时间有关，但多因素分析调整后无显著差异。
阴道地诺前列酮是成功引产的有效方法。孕周、产次和胎儿体重是预测引产至分娩时间间隔的主要因素。
