Euscher Elizabeth D
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard Unit 85, Houston, TX 77030, USA.
Surg Pathol Clin. 2019 Jun;12(2):621-649. doi: 10.1016/j.path.2019.01.005.
Ovarian germ cell tumors are a histologically diverse group of neoplasms with a common origin in the primitive germ cell. The vast majority are represented by mature cystic teratoma. In the minority are malignant germ cell tumors including immature teratoma, dysgerminoma, yolk sac tumor, embryonal cell carcinoma, and choriocarcinoma. This article reviews the histologic and immunohistochemical features of the most common ovarian germ cell tumors. The differential diagnoses for each are discussed.
卵巢生殖细胞肿瘤是一组组织学上多样的肿瘤，起源于原始生殖细胞。绝大多数由成熟囊性畸胎瘤代表。少数为恶性生殖细胞肿瘤，包括未成熟畸胎瘤、无性细胞瘤、卵黄囊瘤、胚胎性癌和绒毛膜癌。本文综述了最常见的卵巢生殖细胞肿瘤的组织学和免疫组化特征。并讨论了每种肿瘤的鉴别诊断。
