Asada M, Tamaki N, Kanazawa Y, Matsumoto S, Matsuo M, Kimura S, Fujii S, Kaneda Y
Neuroradiology. 1978;16:207-11. doi: 10.1007/BF00395251.
Of 53 patients with periventricular lucency, 70% revealed obstructive hydrocephalus, mainly due to infratentorial tumors, and the remainder were cases of communicating hydrocephalus, usually secondary to subarachnoid hemorrhage. Of the patients with PVL, 95% had hypertensive hydrocephalus and 60% showed slightly dilated ventricles. Computer analysis was helpful in displaying PVL objectively and clarifying its nature. In experimentally induced obstructive hydrocephalus, PVL was observed at the acute hypertensive stage. We concluded that the pathogenesis of PVL might be the passive diffusion or acute extravasation of CSF into white matter through the disrupted ventricular wall, rather than transependymal absorption of CSF.
在53例脑室周围透亮区患者中，70%显示梗阻性脑积水，主要由幕下肿瘤引起，其余为交通性脑积水病例，通常继发于蛛网膜下腔出血。在脑室周围透亮区患者中，95%有高血压性脑积水，60%显示脑室轻度扩张。计算机分析有助于客观显示脑室周围透亮区并明确其性质。在实验性诱导的梗阻性脑积水中，在急性高血压阶段观察到脑室周围透亮区。我们得出结论，脑室周围透亮区的发病机制可能是脑脊液通过受损的脑室壁被动扩散或急性渗入白质，而不是脑脊液的经室管膜吸收。
