Murata T, Handa H, Mori K, Nakano Y
Neuroradiology. 1981 Jan;20(5):221-7. doi: 10.1007/BF00342088.
In order to investigate the pathogenesis of periventricular lucency (PVL) in hydrocephalus, CT scans were performed with monitoring of the epidural pressure in a series of dogs with hydrocephalus induced with kaolin. PVL of various degrees was detected in the experimental animals, which disappeared immediately after a shunting operation. Correlations have been attempted between PVL on CT scans and histological examinations, contrast enhancement studies, metrizamide ventriculography, and measurement of regional cerebral blood flow in the periventricular white matter. PVL in hydrocephalus is considered to represent acute edema or chronic CSF retention in the periventricular white matter caused by an increase of water content. In other words, it is regarded as a sign of existing or preceding intraventricular hypertension on CT scan, and seems to be a reversible phenomenon to some extent. PVL may therefore became an indication for a shunt.
为了研究脑积水时脑室周围透亮区（PVL）的发病机制，对一系列用高岭土诱导脑积水的犬进行了CT扫描，并监测硬膜外压力。在实验动物中检测到不同程度的PVL，分流手术后PVL立即消失。已尝试将CT扫描上的PVL与组织学检查、对比增强研究、甲泛葡胺脑室造影以及脑室周围白质区域脑血流量测量进行关联。脑积水时的PVL被认为代表脑室周围白质因含水量增加而出现的急性水肿或慢性脑脊液潴留。换句话说，它在CT扫描上被视为存在或先前存在的脑室内高压的征象，并且在某种程度上似乎是一种可逆现象。因此，PVL可能成为分流的指征。
