1 Center for Healthcare Delivery Science, and.
2 Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Ann Am Thorac Soc. 2019 Jun;16(6):724-730. doi: 10.1513/AnnalsATS.201809-638OC.
Although gastrostomy tubes have shown to be of limited benefit in patients with advanced dementia, they continue to be used to deliver nutritional support in critically ill patients. The epidemiology and short-term outcomes are unclear. To quantify national practice patterns and short-term outcomes of gastrostomy tube placement among the critically ill over the last two decades in the United States. Using the U.S. Agency for Healthcare and Research Quality's Healthcare Cost and Utilization Project's National Inpatient Sample, we evaluated trends in annual population-standardized rates of gastrostomy tube placement among critically ill adults from 1994 to 2014; we also quantified trends in length of stay, in-hospital mortality, and discharge location. We conducted sensitivity analyses among mechanically ventilated patients, survivors, and decedents of critical illness, and in a critically ill population excluding patients with dementia. From 1994 to 2014, population-based rates of gastrostomy tube use in critically ill patients increased from 11.9 to 28.8 gastrostomies per 100,000 U.S. adults (peak in incidence in 2010), an increase of 142% (31,392-91,990 gastrostomy tubes in critically ill patients; < 0.001). Patients receiving gastrostomy tubes during critical illness occupied a growing proportion of all gastrostomy tube placements, accounting for 19.6% of all gastrostomy tubes placed in 1994 and 50.8% in 2014. The rate of gastrostomies in critically ill patients remained roughly stable, from 2.5% of critically ill patients in 1994 to a peak of 3.7% in 2002 before declining again to 2.4% in 2014. Hospital length of stay and in-hospital mortality decreased among gastrostomy tube recipients (28.7 d to 20.5 d, < 0.001; 25.9-11.3%, < 0.001; respectively), whereas discharges to long-term facilities increased significantly (49.6-70.6%; < 0.001). Sensitivity analyses among mechanically ventilated patients revealed similar increases in population-based estimates of gastrostomy tube placement. The incidence of gastrostomy tube placement among critically ill patients more than doubled between 1994 and 2014, with most patients being discharged to long-term care facilities. Critically ill patients are now the primary utilizer of gastrostomy tubes placed in the United States. Additional research is needed to better characterize the long-term risk and benefits of gastrostomy tube use in critically ill patients.
尽管胃造口管在晚期痴呆患者中的益处有限,但它们仍继续被用于为危重症患者提供营养支持。目前尚不清楚其流行病学和短期结果。本研究旨在定量评估美国在过去 20 年中危重症患者胃造口管置管的全国实践模式和短期结果。本研究使用美国医疗保健和研究质量局的医疗保健成本和利用项目国家住院患者样本,评估了 1994 年至 2014 年期间危重症成人中每年人群标准化胃造口管置管率的趋势;还量化了住院时间、院内死亡率和出院地点的趋势。我们在机械通气患者、危重症幸存者和死亡患者以及排除痴呆患者的危重症患者中进行了敏感性分析。1994 年至 2014 年期间,危重症患者胃造口管使用率从每 10 万美国成年人 11.9 例增加到 28.8 例(2010 年达到发病率高峰),增长了 142%(危重症患者中 31392-91990 例胃造口管;<0.001)。在危重病期间接受胃造口管的患者在所有胃造口管放置中的比例不断增加,从 1994 年的 19.6%增加到 2014 年的 50.8%。危重症患者的胃造口管使用率基本保持稳定,从 1994 年的 2.5%上升到 2002 年的 3.7%,然后再次下降到 2014 年的 2.4%。胃造口管接受者的住院时间和院内死亡率均有所下降(28.7 天降至 20.5 天;<0.001;25.9%-11.3%;<0.001),而长期设施的出院率则显著增加(49.6%-70.6%;<0.001)。机械通气患者的敏感性分析显示,胃造口管置管的人群估计值也有类似的增加。1994 年至 2014 年间,危重症患者胃造口管置管的发生率增加了一倍以上,大多数患者出院到长期护理机构。危重症患者现在是美国胃造口管置管的主要使用者。需要进一步研究以更好地描述危重症患者胃造口管使用的长期风险和益处。