Vena Gino A, Cassano Nicoletta, Caccavale Stefano, Argenziano Giuseppe
Dermatology and Venereology Private Practice, Bari, Italy.
Dermatology and Venereology Private Practice, Barletta, Italy.
Dermatol Pract Concept. 2019 Apr 30;9(2):82-89. doi: 10.5826/dpc.0902a02. eCollection 2019 Apr.
The link between anthropometric indices, including height, and cancer risk and/or progression has attracted considerable interest in recent years. Adult height results from the complex interplay between genetic, hormonal, nutritional, and other environmental factors and has been found to contribute to the risk of several selected malignancies, although it has not been implicated as a real cause per se. A number of studies have investigated the height-melanoma relationship, showing controversial results so far. In this review, we summarize the epidemiological data regarding the association between height and melanoma risk and analyze the potential underlying mechanisms.
近年来,包括身高在内的人体测量指标与癌症风险和/或进展之间的联系引起了广泛关注。成人身高是遗传、激素、营养和其他环境因素之间复杂相互作用的结果,尽管它本身并未被视为真正的病因,但已发现其与几种特定恶性肿瘤的风险有关。许多研究调查了身高与黑色素瘤的关系,目前结果存在争议。在本综述中,我们总结了关于身高与黑色素瘤风险关联的流行病学数据,并分析了潜在的潜在机制。