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盆腔放疗对妇科恶性肿瘤膀胱功能的短期影响。

The short-term effect of pelvic irradiation for gynecologic malignancies on bladder function.

作者信息

Farquharson D I, Shingleton H M, Sanford S P, Soong S J, Varner R E, Hester S

出版信息

Obstet Gynecol. 1987 Jul;70(1):81-4.

PMID:3110714
Abstract

Urinary symptoms and urodynamic studies were evaluated prospectively in 33 women undergoing radiation therapy for cervical cancer. Patients were evaluated during treatment, after one to two months, and after five to six months. Significant reductions in peak urinary flow, volume at first desire to void, cystometric capacity, and bladder compliance were evident during and immediately after therapy. Bladder symptoms and urodynamic alteration did not correlate with age, race, or stage of disease. Bladder compliance was significantly reduced in those patients receiving more than 3000 rads to the entire bladder from external beam irradiation.

摘要

对33例接受宫颈癌放射治疗的女性进行了前瞻性的泌尿系统症状和尿动力学研究评估。在治疗期间、治疗后1至2个月以及5至6个月后对患者进行评估。在治疗期间及治疗刚结束后,最大尿流率、首次有排尿意愿时的尿量、膀胱容量及膀胱顺应性均出现显著下降。膀胱症状和尿动力学改变与年龄、种族或疾病分期无关。接受外照射全膀胱剂量超过3000拉德的患者,其膀胱顺应性显著降低。

相似文献

1
The short-term effect of pelvic irradiation for gynecologic malignancies on bladder function.盆腔放疗对妇科恶性肿瘤膀胱功能的短期影响。
Obstet Gynecol. 1987 Jul;70(1):81-4.
2
[Urogynecologic follow-up examinations after radiotherapy of gynecologic malignancies].妇科恶性肿瘤放疗后的泌尿妇科随访检查
Zentralbl Gynakol. 1990;112(15):969-74.
3
[Effect of radiation therapy on urodynamic parameters in cervix cancer patients].[放射治疗对宫颈癌患者尿动力学参数的影响]
Gynakol Rundsch. 1991;31 Suppl 2:249-51.
4
Comparative study of reference points by dosimetric analyses for late complications after uniform external radiotherapy and high-dose-rate brachytherapy for cervical cancer.宫颈癌统一外照射放疗和高剂量率近距离放疗后晚期并发症的剂量学分析参考点比较研究
Int J Radiat Oncol Biol Phys. 2004 Oct 1;60(2):663-71. doi: 10.1016/j.ijrobp.2004.05.028.
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High-dose-rate interstitial brachytherapy for gynecologic malignancies.高剂量率组织间近距离治疗在妇科恶性肿瘤中的应用
Brachytherapy. 2006 Oct-Dec;5(4):218-22. doi: 10.1016/j.brachy.2006.09.002.
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Combined intensity-modulated radiation therapy and brachytherapy in the treatment of cervical cancer.调强放射治疗与近距离放射治疗联合用于宫颈癌的治疗。
Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):618-24. doi: 10.1016/j.ijrobp.2008.02.014. Epub 2008 Apr 11.
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Long-term bladder function in patients with locally advanced cervical carcinoma treated with neoadjuvant chemotherapy and type 3-4 radical hysterectomy.接受新辅助化疗和3-4型根治性子宫切除术治疗的局部晚期宫颈癌患者的长期膀胱功能
Cancer. 2004 May 15;100(10):2110-7. doi: 10.1002/cncr.20235.
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Cervical cancer: combined modality therapy.宫颈癌:综合治疗
Cancer J. 2001 Jul-Aug;7 Suppl 1:S47-50.
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Geometrical sparing factors for the rectum and bladder in the prediction of grade 2 and higher complications after high-dose-rate brachytherapy for cervical cancer.宫颈癌高剂量率近距离放疗后预测2级及以上并发症时直肠和膀胱的几何 sparing 因素。
Int J Radiat Oncol Biol Phys. 2009 Dec 1;75(5):1335-43. doi: 10.1016/j.ijrobp.2008.12.018. Epub 2009 Apr 20.
10
[Intracavitary afterloading radiotherapy--preliminary clinical report on 44 patients].[腔内后装放疗——44例患者的初步临床报告]
Zhonghua Zhong Liu Za Zhi. 1987 Jan;9(1):53-5.

引用本文的文献

1
Prophylactic vesical instillations with 0.2% chondroitin sulfate may reduce symptoms of acute radiation cystitis in patients undergoing radiotherapy for gynecological malignancies.用0.2%硫酸软骨素进行预防性膀胱灌注可能会减轻接受妇科恶性肿瘤放疗患者的急性放射性膀胱炎症状。
Int Urogynecol J. 2011 Jun;22(6):725-30. doi: 10.1007/s00192-010-1357-0. Epub 2011 Mar 2.
2
Post-irradiation bladder dysfunction: development of a rat model.照射后膀胱功能障碍:大鼠模型的建立
Urol Res. 1993;21(6):383-8. doi: 10.1007/BF00300073.