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18F-FDG PET/CT 上表现为恶性肿瘤的 IgG4 相关疾病累及肾盂

Renal Pelvis Involvement of Immunoglobulin G4-Related Disease Mimicking Malignancy on 18F-FDG PET/CT.

机构信息

From the Department of Nuclear Medicine, Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College; and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China.

出版信息

Clin Nucl Med. 2019 Sep;44(9):767-768. doi: 10.1097/RLU.0000000000002621.

Abstract

A 70-year-old woman with bilateral submandibular gland enlargement was referred to our hospital. Submandibular gland biopsy indicated immunoglobulin G4 (IgG4)-related disease (IgG4-RD) involvement. Contrast-enhanced CT was undergone for evaluation of IgG4-RD and revealed a mass located at the left renal pelvis. F-FDG PET/CT showed bilateral FDG-avid submandibular gland and a hypermetabolic mass in the left renal pelvis. The lesions were decreased in both size and metabolism on follow-up PET/CT 2 months after treatment with prednisone. This case illustrated a rare site for IgG4-RD, and the renal pelvis involvement should be considered into differential diagnosis in patients with IgG4-RD history.

摘要

一位 70 岁女性双侧颌下腺肿大,转至我院。颌下腺活检提示 IgG4 相关疾病(IgG4-RD)。为评估 IgG4-RD 行增强 CT 检查,显示左肾盂有一肿块。18F-FDG PET/CT 示双侧颌下腺摄取 18F-FDG 增高,左肾盂有一高代谢肿块。经泼尼松治疗 2 个月后,随访 PET/CT 示双侧颌下腺及左肾盂肿块均缩小,代谢降低。该病例提示 IgG4-RD 可发生于罕见部位,对于有 IgG4-RD 病史的患者,肾盂受累应纳入鉴别诊断。

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