Moghrabi Serin, Abdlkadir Ahmed Saad, Al-Hajaj Nabeela, Gnanasegaran Gopinath, Kumar Rakesh, Syed Ghulam, Bozkurt Murat Fani, Shukri Saad, Obeidat Shahed, Khalaf Aysar, Shahait Mohammed, Al-Nabhani Khalsa, Al-Ibraheem Akram
Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Amman 11941, Jordan.
Department of Nuclear Medicine, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
J Clin Med. 2024 Aug 7;13(16):4632. doi: 10.3390/jcm13164632.
Non-tumorous kidney diseases include a variety of conditions affecting both the structure and function of the kidneys, thereby causing a range of health-related problems. Positron emission tomography/computed tomography (PET/CT) has emerged as a potential diagnostic tool, offering a multifaceted approach to evaluating non-tumorous kidney diseases. Its clinical significance extends beyond its conventional role in cancer imaging, enabling a comprehensive assessment of renal structure and function. This review explores the diverse applications of PET/CT imaging in the evaluation of non-cancerous kidney diseases. It examines PET/CT's role in assessing acute kidney injuries, including acute pyelonephritis and other forms of nephritis, as well as chronic conditions such as immune complex-mediated glomerulonephritis and chronic kidney disease. Additionally, the review delves into PET/CT's utility in evaluating complications in renal transplant recipients, identifying renal histiocytosis and detecting renal amyloidosis. The current review aims to promote further research and technological advancements to popularize PET/CT's clinical utility in diagnosing and treating non-tumorous kidney diseases.
非肿瘤性肾脏疾病包括多种影响肾脏结构和功能的病症,从而导致一系列与健康相关的问题。正电子发射断层扫描/计算机断层扫描(PET/CT)已成为一种潜在的诊断工具,为评估非肿瘤性肾脏疾病提供了多方面的方法。其临床意义超出了其在癌症成像中的传统作用,能够对肾脏结构和功能进行全面评估。本综述探讨了PET/CT成像在评估非癌性肾脏疾病中的各种应用。它研究了PET/CT在评估急性肾损伤中的作用,包括急性肾盂肾炎和其他形式的肾炎,以及慢性疾病,如免疫复合物介导的肾小球肾炎和慢性肾脏病。此外,该综述还深入探讨了PET/CT在评估肾移植受者并发症、识别肾组织细胞增多症和检测肾淀粉样变性方面的效用。当前的综述旨在促进进一步的研究和技术进步,以推广PET/CT在诊断和治疗非肿瘤性肾脏疾病中的临床效用。