Department of Neurology, Cork University Hospital, Ireland.
Department of Histopathology, Cork University Hospital, Ireland.
J Neuroimmunol. 2019 Aug 15;333:476955. doi: 10.1016/j.jneuroim.2019.04.015. Epub 2019 Apr 30.
We present a case of a drug-induced sarcoidosis -like reaction (DISR) occurring following initiation of Natalizumab for multiple sclerosis. The reaction was purely cutaneous, and disappeared following drug withdrawal. We highlight this case to the practicing neurologists, with warning to be wary of a new rash on immunomodulatory therapies.
我们报告了一例在使用那他珠单抗治疗多发性硬化症后发生的药物诱导的类肉瘤样反应(DISR)。该反应为单纯皮肤型,停药后消失。我们向神经内科医生强调了这种情况,并警告他们在免疫调节治疗中要警惕新出现的皮疹。