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三叉神经营养综合征——一种罕见病症的独特临床表现

Trigeminal Trophic Syndrome-A Unique Clinical Presentation of a Rare Condition.

作者信息

Bradburn Kathryn H, Elston Dirk, Murphey Alexander W, Patel Krishna G

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.

Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA.

出版信息

Ear Nose Throat J. 2019 Dec;98(10):606-608. doi: 10.1177/0145561319850818. Epub 2019 May 23.

DOI:10.1177/0145561319850818
PMID:31119987
Abstract

This study describes a unique clinical presentation of trigeminal trophic syndrome (TTS), which is not well described within the otolaryngology literature. Trigeminal trophic syndrome classically presents with a triad of symptoms: trigeminal anesthesia, facial paresthesias, and crescent-shaped ulceration of the lateral nasal ala. The patient discussed in this report had a self-induced, waxing and waning ulceration of the frontal scalp for 7 years and was evaluated and treated ineffectively by multiple physicians, including otolaryngologists, before TTS was diagnosed and a targeted treatment was initiated. Although extranasal presentation is uncommon, this condition must be considered when ulcers are encountered in the trigeminal dermatome. This case highlights the variability in presentation and the importance of awareness of this rare syndrome. We aim to facilitate more prompt diagnosis and expedite the initiation of appropriate treatment for TTS in the field of otolaryngology.

摘要

本研究描述了一种独特的三叉神经营养综合征(TTS)临床表现,这在耳鼻喉科文献中尚无详尽描述。三叉神经营养综合征典型表现为三联征:三叉神经感觉缺失、面部感觉异常以及鼻翼外侧的新月形溃疡。本报告中讨论的患者前额头皮出现自伤性、时好时坏的溃疡长达7年,在被诊断为三叉神经营养综合征并开始针对性治疗之前,包括耳鼻喉科医生在内的多位医生对其进行了评估和治疗,但均未取得有效效果。尽管鼻外表现并不常见,但在三叉神经皮节出现溃疡时必须考虑到这种情况。该病例突出了临床表现的变异性以及认识这种罕见综合征的重要性。我们旨在促进耳鼻喉科领域对三叉神经营养综合征更迅速的诊断并加快启动适当治疗。

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