Scheper Henk, Wouthuyzen-Bakker Marjan, Veldkamp Karin Ellen, van der Wal Robert J P, Vogely H Charles, de Boer Mark G J
LUMC, afd. Infectieziekten, Leiden.
Contact: H. Scheper (
Ned Tijdschr Geneeskd. 2019 May 16;163:D3734.
Prosthetic joint infection A prosthetic joint infection (PJI) is a serious complication that can lead to lengthy hospitalization, significant limitations in mobility, and a reduced quality of life. For acute PJI, the aim is to cure the infection whilst retaining the prosthesis; this can be achieved by means of thorough surgical debridement, cleaning of the artificial material, replacement of exchangeable prosthesis parts and adjuvant antibiotic therapy. In cases of chronic PJI, the prosthetic joint needs to be replaced. For patients in whom surgery is not feasible, or who refuse surgical intervention, chronic suppressive antibiotic therapy can be applied if the infection persists. In order to increase the likelihood of a favourable outcome, it is important to take a multidisciplinary approach.
人工关节感染 人工关节感染(PJI)是一种严重的并发症,可导致长期住院、行动严重受限以及生活质量下降。对于急性PJI,目标是在保留假体的同时治愈感染;这可以通过彻底的手术清创、清洁人工材料、更换可替换的假体部件以及辅助抗生素治疗来实现。对于慢性PJI病例,需要更换人工关节。对于手术不可行或拒绝手术干预的患者,如果感染持续存在,可以采用长期抑制性抗生素治疗。为了提高获得良好结果的可能性,采取多学科方法很重要。